Important Safety Information
to Consider about Rebif
Rebif has a well-established safety profile
You and your doctor should weigh all the risks and benefits before starting a treatment.
Potential serious side effects of Rebif include depression and risk of suicide, liver problems, risk to pregnancy, injection-site problems, and severe allergic reactions. Allergic reactions are rare and may be associated with difficulty in breathing and loss of consciousness, which require immediate medical attention.
The most common side effects with Rebif are injection-site reactions, flu-like symptoms (fever, chills, muscle aches, tiredness), depression, abdominal pain, increased liver enzymes, and blood cell count decreases. Let your doctor know if you have any of these symptoms or feel sad, tired, hot or cold, or experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).
This information is not intended to replace discussions with your doctor. For additional information about Rebif, please consult the Prescribing Information and Medication Guide and talk to your doctor.
You can also visit www.MSLifeLines.com or call toll-free 1-877-44-REBIF (1-877-447-3243). Rebif is available by prescription only.
- Rebif has not been adequately studied in pregnant women. Rebif is not recommended for women who are or plan to become pregnant
Indication
Rebif is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS. Rebif is not approved for treatment of chronic progressive MS. Rebif is available in 22 mcg and 44 mcg prefilled, preassembled syringes and a titration pack.
Important safety information
Before beginning treatment, patients should discuss with their doctor the potential benefits and risks associated with Rebif. Let your doctor know if you have a history of depression, seizures, liver disease, thyroid problems, or blood cell count or bleeding problems, or if you have had previous allergic reactions to medications. Tell your doctor about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Rebif and other medicines may affect each other causing serious side effects. Talk to your doctor before you take any new medicines. Rebif is not recommended for women who are or plan to become pregnant.
Potential serious side effects of Rebif include depression and risk of suicide, liver problems, risk to pregnancy, injection-site problems, and severe allergic reactions. Allergic reactions are rare and may be associated with difficulty in breathing and loss of consciousness, which require immediate medical attention.
The most common side effects with Rebif are injection-site reactions, flu-like symptoms (fever, chills, muscle aches, tiredness), depression, abdominal pain, elevated liver enzymes, and blood abnormalities.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
This information is not intended to replace discussions with your doctor. For additional information about Rebif, please consult the Medication Guide and talk to your doctor. You can also visit www.mslifelines.com or call toll-free 1-877-447-3243. Rebif is available by prescription only.
Rebif and MS LifeLines are registered trademarks of EMD Serono, Inc. or its affiliates.
Brought to you by EMD Serono, Inc. and Pfizer Inc, the co-marketers of
Rebif® (interferon beta-1a) in the US.
Prescribing Information (PDF) - Medication Guide (PDF)
This information is intended only for residents of the United States.
Copyright © 2011 EMD Serono, Inc. All rights reserved.
EMD Serono, Inc., One Technology Place, Rockland, MA 02370
WebMD does not endorse any specific product, service, or treatment.
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