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What Is Churg-Strauss Syndrome?

Treatment continued...

Corticosteroids, usually called "steroids," are the most common drugs doctors prescribe for this condition. Most people with it take prednisone (by mouth) and prednisolone (by IV). People whose nervous system, heart, kidneys, or intestines are not affected do very well with prednisone alone.

In some cases, doctors also prescribe chemotherapy medications -- such as azathioprene (Imuran), cyclophosphamide (Cytoxan), or methotrexate. Chemo drugs are powerful medicines used to treat cancer. Churg-Strauss syndrome is not cancer, so you would probably take a lower dose than someone who has cancer. While you take these drugs, you will likely get blood tests often to check for any side effects.

Once the disease is under control, doctors slowly lower the dose of prednisone and eventually stop it entirely, if possible. If you also take chemotherapy drugs, your doctor may ease you off of it after your condition is under control. This often takes at least 6 months or up to several years.

What Is the Outlook for People With Churg-Strauss Syndrome?

In most people with the disease (more than 90%), the symptoms will disappear with treatment. This is called remission. The best results tend to happen when your doctor knows a lot about the condition and starts treatment ASAP.

People who have severe kidney, heart, intestinal tract, or brain inflammation usually do not do as well as those with milder forms of the disease that affect only the skin, joints, lungs, nose, sinuses, and ears. But when treated promptly, even people with the most severe forms of CSV can expect to get better.

WebMD Medical Reference

Reviewed by David Zelman, MD on October 19, 2014
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