Nearly every arthritis sufferer has taken a traditional painkiller like
aspirin or Aleve. They are a great solution for relieving pain and
inflammation, but there's a definite downside. These drugs often lead to more
trouble including upset stomach and bleeding ulcers.
There are some 20 traditional nonsteroidal anti-inflammatory drugs or
NSAIDs, including aspirin, ibuprofen (Advil and Motrin), naproxen (Aleve),
indomethacin (Indocin), and piroxicam (Feldene).
In every issue of WebMD the Magazine, we ask our experts to answer readers' questions about a wide range of topics. In our May 2011 issue, a reader with rheumatoid arthritis asked WebMD's rheumatology expert, Scott Zashin, MD, why her husband doesn't help her more.
These drugs can bother the GI tract in a number of different ways, says
Robert Hoffman, MD, chief of rheumatology at the University of Miami Miller
School of Medicine. "Gastritis, esophageal reflux disease [heartburn or
GERD], and bleeding ulcers are all problems that can develop from
Though there are a few things you can do to reduce stomach upsets, there are
no guarantees that serious problems won't develop - serious enough to mean
hospitalization and even death, he adds. Older people with other medical
problems are at especially increased risk.
"If you're taking NSAIDs on a chronic basis, there's a very high
percentage risk that you will develop significant symptoms," says Hoffman.
The bottom line: "Don't treat an arthritis problem on your own. See a
To keep yourself safe:
Use short term only. The FDA advises that over-the-counter
NSAIDs be taken only for 10 days or so. Some people can control their pain this
way, with no serious risks.
Take with food and water. Taking painkillers with a glass
of water and a bit of food seems to ease stomach upsets. Sometimes taking an
NSAID with an antacid or calcium supplement can help.
Stop bad habits. Alcohol and cigarette smoking will up your
risk of stomach problems.
Change time of day. Taking an NSAID in the afternoon or
evening sometimes eases stomach upsets.
Check with your pharmacist. Are you taking other
medications besides an NSAID? Some medications taken together can increase your
risk of side effects. For instance, a blood thinner like Coumadin plus an NSAID
can increase your risk of bleeding. Talk with your pharmacist or a doctor if
you're taking another medication and an NSAID.