Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Select An Article

What Are NSAIDs for Rheumatoid Arthritis?

Font Size

NSAIDs -- or nonsteroidal anti-inflammatory drugs -- are commonly used to treat rheumatoid arthritis. They help manage the chronic pain, inflammation, and swelling tied to RA.

They do not slow down the disease. Most people with RA also take other types of medications, such as methotrexate or biologics, to help prevent further joint damage.

How Do NSAIDs Work?

They block your body’s “Cox” enzymes. This cuts down on inflammation and reduces pain and stiffness.

What Are Some NSAIDs Used for Rheumatoid Arthritis?

These include:

Arthrotec is an NSAID that combines diclofenac with another active ingredient, misoprostol, to help prevent stomach irritation.

Prevacid Naprapac combines naproxen with the acid blocker Prevacid to lower your chances of getting stomach ulcers.

Vimovo is a combination of naproxen and the acid blocker Nexium.

Do All NSAIDs Raise the Risk of Heart Attack and Stroke?

All prescription NSAIDs are linked to a higher risk of heart attack and stroke. They carry a warning about that.

While the actual risk of a heart attack and stroke with NSAIDs is unknown, medical studies are in progress to help find that answer. The risk is likely greatest for people who have heart disease risk factors, such as high blood pressure, high cholesterol, diabetes, and smoking.

You and your doctor can weigh the risks and benefits.

What Are the Side Effects?

The most common ones include:

NSAIDs may also raise blood pressure. If you have high BP, keep a close eye on your blood pressure. Let your doctor know if it goes up.

Most people take these meds with few to no side effects, though.

Next Article:

Today on WebMD

rubbing hands
Avoid these 6 common mistakes.
mature couple exercising
Decrease pain, increase energy.
mature woman threading needle
How much do you know?
Swelling, fatigue, pain, and more.
Lucille Ball
Hand bones X-ray
prescription pills
Woman massaging her neck
woman roasting vegetables in oven
Woman rubbing shoulder
doctor and patient hand examination