Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier
WebMD

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine
WebMD

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion
    WebMD

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community
    WebMD

    Community

    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Font Size
A
A
A

Rheumatoid Arthritis Drug May Improve Function

Experimental Drug Orencia May Help Relieve RA Symptoms, Study Shows
By
WebMD Health News

Sept. 14, 2005 -- The experimental rheumatoid arthritis drug Orencia is safe and effective, researchers report in The New England Journal of Medicine.

The researchers show that Orencia offered pain relief and increased movement in arthritis patients who had exhausted other treatment options.

"This drug works where others haven't," researcher Mark Genovese, MD, says in a news release. He is the associate chief of the immunology and rheumatology division at Stanford's medical school and an associate professor of medicine at Stanford.

Several of the study's researchers, including Genovese, have served as employees or paid consultants for Orencia's maker, Bristol-Myers Squibb. The study was sponsored in part by Bristol-Myers Squibb. The company is a WebMD sponsor.

An FDA advisory panel recently recommended Orencia for approval. The FDA often follows the advice of its advisory panels but isn't required to do so.

The study was reviewed by the FDA advisory panel, states the news release.

First in a New Class of Drugs

Orencia is the first in a new class of rheumatoid arthritisrheumatoid arthritis drugs, note Genovese and colleagues.

In rheumatoid arthritis, the body's immune system attacks cells in joints. That can cause pain, stiffness, and swelling of the joints. Over time, it can lead to cartilage breakdown, bone loss, joint weakness, and disability.

The immune system is targeted by several current rheumatoid arthritis drugs. Those drugs work and have helped many people. But some patients don't respond to those drugs, note Genovese and colleagues.

Orencia also focuses on the immune system. It blocks a signal from the immune system's T-cells, which are needed to activate many of the cells of the immune system and play an important role in the development of rheumatoid arthritis.

Today on WebMD

rubbing hands
Avoid these 6 common mistakes.
mature couple exercising
Decrease pain, increase energy.
 
mature woman threading needle
How much do you know?
hands
Swelling, fatigue, pain, and more.
 
Lucille Ball
Slideshow
Hand bones X-ray
Article
 
prescription pills
Article
Woman massaging her neck
Quiz
 
woman roasting vegetables in oven
Slideshow
Woman rubbing shoulder
Slideshow
 
doctor and patient hand examination
Video
arthritis
Article