Skip to content

Drug Combo Best for Rheumatoid Arthritis

Combination Treatment Works Best for Preventing Future Complications
Font Size
A
A
A

Patients With Best Results continued...

"Patients in groups 3 and 4 had the benefit of a more rapid relief of symptoms and improvement of physical function," says researcher B. A. C. Dijkmans, MD, of VU Medical Center in Amsterdam, The Netherlands, in a news release. "In addition, there is the possibility that effective suppression of disease activity during the early phases of the disease may ameliorate the long-term joint damage and poor physical function and, ideally, even induce true clinical remission without the need for ongoing DMARD treatment."

The number of rheumatoid arthritis patients in these two groups without any progression of their disease was also higher than in the other two groups.

Overall, researchers say people who received initial combination rheumatoid arthritis treatment experienced no more side effects than the other groups.

Methotrexate can cause severe toxicity to the liver and bone marrow. Regular monitoring of blood counts and liver enzymes is standard during treatment. Methotrexate can also produce injury to the lungs and the GI tract. Pregnant women and those that are planning on being pregnant should not take this medication.

Remicade use has been associated with severe liver injury, decreased blood counts, and development of lymphoma (a kind of cancer). It should not be used if you are suffering from certain other medical conditions.

Both medications have immune-suppressing activity which can make a person more susceptible to infections, particularly opportunistic infections that can be fatal.

1 | 2

Today on WebMD

rubbing hands
Avoid these 6 common mistakes.
woman roasting vegetables in oven
Four that fight inflammation.
 
mature woman threading needle
How much do you know about these RA myths and facts?
Patients who take the product would get no
This may lead to worsening symptoms.
 
Lucille Ball
Slideshow
Hand bones X-ray
Article
 
prescription pills
Article
Woman massaging her neck
Quiz
 
woman roasting vegetables in oven
Slideshow
Woman rubbing shoulder
Slideshow
 
Working out with light weights
Video
arthritis
Article