Woman with rheumatoid arthritis in her hand
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What Is Rheumatoid Arthritis (RA)?

Rheumatoid arthritis is an immune system condition, or “autoimmune disorder,” that causes inflammation of the lining of the joints. It may also affect the skin, eyes, lungs, heart, blood, and nerves. Although RA symptoms can come and go, the disease can worsen over time and may never go away. Early, aggressive treatment is key to slowing or stopping it.

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Rheumatoid nodules on the fingers
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What Are the Symptoms?

Joint inflammation from RA comes with pain, warmth, and swelling. The inflammation is typically symmetrical, occurring on both sides of the body at the same time (such as the wrists, knees, or hands). Other symptoms of RA include joint stiffness, particularly in the morning or after periods of inactivity; ongoing fatigue, and low-grade fever. Symptoms typically develop gradually over years, but they can come on rapidly for some people.

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Woman with RA driving easy-to-shift car
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Who Gets It?

It usually strikes between ages 30-60, but younger and older people can get it. About 1% of the U.S. population has the condition, which is two to three times more common in women than in men. You’re more likely to get it if you smoke or if you have a relative who has this disease.

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T Cell Resting on a Dendritic Cell
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What Causes It?

Scientists don’t know exactly why people get RA. Some people may have a genetic risk for it that gets triggered by a particular infection that experts haven’t yet identified.

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Hand with swollen, arthritic knuckles
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How Does It Affect the Joints?

Inflammation of the lining of the joints can destroy cartilage and bone, deforming the affected joints. As the condition progresses, joints can become painful and not work as well.

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Rheumatoid arthritis nodules on elbow
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What Does It Do to the Rest of the Body?

RA can affect organs and areas of the body other than the joints, including:

  • Rheumatoid nodules (shown here): firm lumps under the skin and in internal organs  
  • Sjogren's syndrome: inflammation and damage of the glands of the eyes and mouth; other parts of the body can also be affected
  • Pleuritis: inflammation of the lining of the lungs
  • Pericarditis: inflammation of the lining surrounding the heart
  • Anemia: not enough healthy red blood cells
  • Felty syndrome: not enough white blood cells. Also linked to ah enlarged spleen.
  • Vasculitis: blood vessel inflammation, which can hamper blood supply to tissues
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child's hands with juvenile rheumatoid arthritis
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What Is Juvenile Rheumatoid Arthritis (JRA)?

Juvenile RA is the most common type of arthritis in kids. Like adult RA, it causes joint inflammation, stiffness, and damage. However, it can also affect a child's growth. Juvenile RA is also known as juvenile idiopathic arthritis. "Idiopathic" means the cause is unknown.

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Pregnant young woman wearing sun hat
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RA and Pregnancy

Surprisingly, rheumatoid arthritis improves in up to 80% of women during pregnancy. It will likely flare up after the baby is born. Why this happens is unclear. You may need to make changes in your medication before you conceive and during pregnancy.

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examining hand for signs of rheumatoid arthritis
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What Doctors Will Check On

Because symptoms may come and go, diagnosing RA in its early stages is challenging. If you have these symptoms, your doctor may order further tests:

  • Morning joint stiffness
  • Swelling/fluid around several joints at the same time
  • Swelling in the wrist, hand, or finger joints
  • Same joints affected on both sides of your body
  • Firm lumps under the skin (rheumatoid nodules)

 

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Doctor drawing blood from patient for testing
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Blood Tests You May Get

If your doctor thinks you have RA, she may give you blood tests to check for signs of inflammation in the body. Other common tests are for rheumatoid factor (RF) and “anti-CCP” (anti-cyclic citrullinated peptide), which most people with RA have. There is no single test for RA, though.

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X-ray of rheumatoid arthritis
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Imaging Tests You may May Get

X-rays can help diagnose RA and provide a baseline for comparison later as the disease progresses. You may also get an MRI or ultrasound to look for joint damage and inflammation.

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Doctor and an Elderly Woman Talking
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Treatments for RA

Although there is no cure, treatment can lower joint inflammation and pain, prevent joint damage, and help keep your joints working. You should start ASAP. Your doctor will make a plan based on your particular case, including your age, affected joints, and how severe the disease is. It will include medication and exercise to strengthen muscles around the joints. Some people need surgery.

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Woman holding hand out with pills in palm
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Medicines

Medications used to treat RA include drugs that slow or stop the disease, steroids, and pain relievers. You may need to take more than one type of drug. For instance, you may take one for pain and another to protect your joints from further damage.

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Colored X-ray showing replacement  of knee joints
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Is Surgery an Option?

If you have a lot of joint damage or pain, your doctor may suggest surgery. Joint replacement (especially hips and knees) is the most common type for people with RA. Other types of surgery include arthroscopy (inserting a tube-like instrument into the joint to see and repair damage) and tendon reconstruction.

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three acupuncture needles near the elbow
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Other Treatments

Some people with RA get relief from using moist heat, acupuncture, and relaxation. Supplements that have been shown to possibly help RA are fish oil, borage seed oil, and cat's claw. Check with your doctor before you start supplements as they can cause side effects and may interact with your medications.

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Woman picking cherry tomato off of salad
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What About Diet?

Although there's no "rheumatoid arthritis diet,” many people with RA find that eating or avoiding certain foods helps their symptoms. Foods high in saturated fats (bacon, steak, butter) raise inflammation in the body. Omega-3 fatty acids (salmon, tofu, walnuts) may be helpful. Some people feel that other foods -- such as tomatoes, citrus fruits, white potatoes, peppers, coffee, and dairy -- worsen RA symptoms.

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Dive In!

Regular exercise can help those stiff, painful joints. It also keeps bones and muscles strong. Choose exercises such as gentle stretching, resistance training, and low-impact aerobics (swimming, water aerobics). Use caution with any activity that puts pressure on the joints, like jogging or heavy weight lifting. When you have a flare, take a short break from exercise. If you are not active now, talk to your doctor before you get started.

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Sources | Medically Reviewed on 08/23/2016 Reviewed by Debra Jaliman, MD on August 23, 2016

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REFERENCES:

National Institutes of Arthritis and Musculoskeletal and Skin Diseases: “Rheumatoid Arthritis.”

Arthritis Foundation: "Rheumatoid Arthritis: What Is It?", "Rheumatoid Arthritis: What Causes It?", "Rheumatoid Arthritis: Who Gets It?", "Rheumatoid Arthritis: How Is It Diagnosed?", "Rheumatoid Arthritis: Treatment Options," "More Than Just Joints: How Rheumatoid Arthritis Affects the Rest of Your Body," "Juvenile Rheumatoid Arthritis?"

Johns Hopkins Arthritis Center: "Rheumatoid Arthritis Pathophysiology."

UpToDate.com: "Patient Information: Rheumatoid Arthritis and Pregnancy."

Natural Medicines Comprehensive Database.

National Center for Complementary and Alternative Medicine: "Rheumatoid Arthritis and Complementary and Alternative Medicine."

Reviewed by Debra Jaliman, MD on August 23, 2016

This tool does not provide medical advice. See additional information.

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.