Rheumatoid arthritis primarily affects the joints but
can also affect the whole body, causing what are called systemic symptoms.
These systemic symptoms occur especially in people who have severe
It is possible that the main title of the report Arthritis, Juvenile Rheumatoid is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Blood and blood vessels. Low levels of white
blood cells (leukopenia) and red blood cells (anemia) as well
as spleen enlargement (an organ involved in making blood and immune cells) may
occur. When these problems occur together, it is called Felty's syndrome.
Inflammation can also affect the blood vessels (vasculitis),
causing open sores (ulcers) of the skin. And people who have rheumatoid arthritis seem to develop plaque deposits in arteries (atherosclerosis) earlier than people who do not have rheumatoid arthritis.
and muscles. There may be a loss of strength in muscles next to affected
joints. Inflammation may also cause pressure on the nerves (compression). An
example is compression of one of the nerves in the wrist, which affects
sensation in the thumb, index, and middle fingers. This is called
carpal tunnel syndrome.