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    Love on the Brain

    Scientists peeking inside our brains and psyches have more clues than ever about the biology of love -- why we're attracted, why we fall so hard, and what makes us stay.

    The Biology of Love: Your Brain in Love

    Love involves three basic brain circuits, according to Fisher. There's the sex drive, which motivates us to seek out partners; romantic love, the in-the-clouds feeling when you first fall in love; and the attachment phase, the comfortable-but-fewer-fireworks stage.

    "The sex drive is a very simple drive," Fisher says. "It's simply the craving for sexual gratification, driven largely by testosterone in both men and women."

    The three brain systems, however, don't always come into play in any kind of order. They can kick in separately of be intertwined. Or they can trigger each other. For instance: you can have sex with someone but not fall in love, of course; you can be in love with someone with whom you've never had sex.

    "Of these three systems, in many respects I think the most powerful one is intense romantic love," Fisher says. With Aron and others, Fisher has used functional magnetic resonance imaging (fMRIs) to examine the brains of people in love and get clues about romantic love.

    In one study, 17 people who were newly in love and asked to look at a photo of their beloved showed intense activity in two brain regions associated with reward and motivation -- called the ventral tegmental area and the right caudate nucleus. The findings led Fisher's team to suggest that the crazy-in-love feeling is more a motivation system than an emotion. The report was published in 2005 in The Journal of Comparative Neurology.

    "Both the VTA and the caudate nucleus are part of the brain reward system," Fisher says. And the VTA, she says, is a "mother lode" for cells that make dopamine, a brain chemical important for controlling emotional response and the ability to feel pleasure and pain. As dopamine levels in the madly-in-love increase, she says, it accounts for focused attention on the new partner, motivation to get the reward -- and the lover's high.

    In this romantic love phase, Fisher says, lovers are motivated to win each other over. Obsessive thinking is part and parcel.

    "What we are seeing is activation in the same area as when you expect to receive a large reward," Aron says. It's the same area that "lights up" in cocaine users, he says, as they anticipate using the drug.

    "What we think is what's going on when one falls in love is, one perceives incredible opportunities for one's life to be enriched," Aron says. "Perhaps the most important reward for most people is falling in love."

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