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Birth Control Health Center

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Warning Added to Birth Control Patch

Ortho Evra Patch Exposes Women to More Estrogen Than Birth Control Pills; May Raise Risk of Blood Clots, Says FDA
WebMD Health News

Nov. 11, 2005 -- Ortho Evra, the birth control skin patch, will get a new bolded warning stating that the patch provides a higher exposure to estrogen than birth control pills.

"Higher levels of estrogen may put some women at increased risk for getting blood clots," states the FDA.

The FDA provided these questions and answers about the new warning:

What is the FDA announcing?
The FDA is announcing a revision to the label for the drug Ortho Evra, the only skin patch approved for birth control. This change includes a new bolded warning about higher exposure to estrogen for women using the weekly patch compared with taking a daily birth control pill containing 35 micrograms of estrogen, a commonly prescribed dose. Higher levels of estrogen may put some women at increased risk for getting blood clots. When thinking about prescribing or using Ortho Evra, health care professionals and women need to balance the increased exposure to estrogen against the chance of pregnancy if a birth control pill is not taken daily.

Why is the FDA making this announcement?
A woman on Ortho Evra may be exposed to approximately 60% more estrogen than if she was taking a typical 35 microgram estrogen birth control pill. There are also high-dose estrogen pills on the market, such as the 50-microgram birth control pills, and some women need these. Estrogen use is linked to blood clots in the legs and lungs and other clotting problems such as strokes and heart attacks. It is not known if women using Ortho Evra have a higher risk of serious side effects than women taking the typical 35-microgram estrogen pills.

How does the increase in exposure of estrogen affect me when taking Ortho Evra?
In general, a woman may be at higher risk for getting side effects if she takes higher doses of estrogen. However, it is not known if a woman using the Ortho Evra patch is at higher risk for serious side effects than if she is using a typical birth control pill. Women should discuss with their health care professional whether the Ortho Evra patch is a good method of contraception for them.

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