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Reviewed By: Varnada Karriem-Norwood,
SOURCES: 2008 Medical Reference from Medstar. Juan Bailey, MD, HIV Specialist, Beth Israel Medical Center, New York, NY.
© 1999-2011 Medstar Television
When it comes to HIV, Edward Barnes has seen it all
I've had HIV for 24 years. Yeah, it's been a long journey.
Because Edward's had the virus for so long, he's tried nearly every drug to keep it under control.
So at a point maybe two or three years ago I had, I had become resistant to absolutely everything that was out there.
Multi-drug resistance is a common problem that's caused when HIV replicates itself with mutations.
We started having much more of a challenge in trying to come up with a medication that individuals may be sensitive to them.
Now, a new drug called Isentress (eye SENN tress), may help by cutting off HIV replication. It blocks an enzyme called integrase (INN tuh grace) that helps the virus merge its genetic material into the immune system's cells.
The virus can't get into the host DNA. It can't incorporate itself there and then utilize the machinery of the cell to make more viruses. So that stops the process.
By interrupting the replication process, the amount of virus in the body drops.
The viral load, something we can actually measure in the, in the blood, actually goes down substantially.
It's made a remarkable difference since Edward added it to his drug cocktail.
I've remained undetectable for the first time in my life it's been able to be sustained, that has truly been a life-changing thing.
Due, it's believed, to a drug that's helping crush the resistance. For WebMD, I'm Damon Meharg.
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