People at high risk of contracting syphilis include those
Have unprotected sex (do not use condoms or
do not use them correctly). This risk is especially high among men who have sex
with men (MSM).5
Have multiple sex partners, particularly if they live in
an area of the country where syphilis is more common.
Have a sex
partner who has syphilis.
Have sex with a partner who has multiple
Exchange money or drugs for sex
Have human immunodeficiency virus (HIV) infection.
The U.S. Centers for Disease Control and Prevention (CDC) and the
U.S. Preventive Services Task Force strongly recommend
that pregnant women be screened for syphilis because of the severe consequences
of being pregnant while infected or having a child born with
congenital syphilis. Screening should be done:2, 3
At the first prenatal visit for all pregnant
During the third trimester and again at delivery for
pregnant women who have an increased risk for syphilis.