This article is from the WebMD Feature Archive
Can You Beat Cellulite?
Perhaps nothing is cuter than a pair of dimples accentuating your smile. But it's not so cute when dimples turn up on your thighs, buttocks, tummy, and upper arm.
The problem is cellulite, fatty deposits of dimpled skin that can appear on even the most fabulously thin body.
"That's because cellulite is not a fat problem, it's a skin problem. It has nothing to do with what you weigh, or how much weight you lose," says Hollywood dermatologist Howard Murad, MD, author of The Cellulite Solution.
The fat that causes cellulite is not the same as the fat that takes us from a size 10 to a 14, experts say. That fat lies far below the skin, closer to our bones, and it is what the body burns as fuel for energy.
Cellulite, on the other hand, is made up of fat cells that reside within the skin. They can't be burned as fuel, says Murad, so dieting, exercise, even liposuction won't help.
Cellulite is a decidedly womanly problem, primarily targeting females over 35. Although doctors aren't sure why, many say hormones and anatomy are key.
"The best evidence for increased incidence in women is that it's related to hormonal changes, but also the anatomy of what's called 'septa' -- fibrous bands of tissue that surround fat cells in the skin to help keep them in place," says Bruce Katz, MD, medical director of Juva Skin and Laser Center in New York, and clinical professor of dermatology at the Mt. Sinai School of Medicine.
In men, Katz says, the septa run in a diagonal pattern, while in women, their pattern is vertical.
When we are young, this doesn't matter, since both designs work equally well in keeping cellulite anchored within the deeper layers of skin. As we age, however, the normally elastic septa can become hard and rigid. When they do, they bear down on the buoyant cellulite cells, which begin pushing up through the spaces of the hardened septa pattern.
"When the septa run vertically, it results in a 'mattress tufting' effect,'" Katz tells WebMD. "The fat cells push up in between and create those dimples we know as cellulite."
Got Cellulite? Blame Mom!
For generations, doctors have said cellulite was here to stay -- a lumpy, bumpy rite of passage to womanhood that we just had to learn to live with.
But in the last 20 years several treatment options have emerged. While the science is still shaky, with few studies to attest to the effects, some experts report significant results -- at least anecdotally.
To help you get a handle on what's available, our three experts discussed the possibilities.
Option 1: Creams and Lotions
Arguably the easiest and least-costly approach is lotions and creams that purport to stimulate cell circulation, melt fat, and move fluid and toxins out. Many doctors are not convinced they help. But Newburger says there are creams and lotions that have some effect -- those whose key ingredient is methylxanthines (one form of which is caffeine).
VIVELLE-DOT (estradiol transdermal system) IS AVAILABLE BY PRESCRPTION ONLY.
INDICATION
Vivelle-Dot is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; help reduce your chances of getting osteoporosis (thin weak bones); and treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally. Vivelle-Dot 0.025 mg/day is only used to prevent osteoporosis from menopause. If you use Vivelle-Dot only to treat your dryness, itching, and burning in and around your vagina or if you use Vivelle-Dot only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.
IMPORTANT SAFETY INFORMATION
Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia (decline in memory and thinking skills).
Vivelle-Dot should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.
The most common side effects that may occur with Vivelle-Dot are headache, breast tenderness, and back pain.
You and your healthcare professional should talk regularly about whether you still need treatment with Vivelle-Dot.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information for Vivelle-Dot.

