It is possible that the main title of the report Cutis Laxa is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Chalasodermia, Generalized
- Chalazodermia, Generalized
- Dermatochalasia, Generalized
- Dermatolysis, Generalized
- Elastorrhexis, Generalized
- Occipital Horn Syndrome
- Congenital Cutis Laxa Syndrome
- Acquired Cutis Laxa Syndrome
- Cutis Laxa , X-linked (formerly known as Ehlers Danlos IX)
- Cutis Laxa, X-linked (formerly known as Ehlers Danlos IX)
Cutis laxa is rarely encountered and may occur in several inherited (congenital) forms or come about in the course of another disorder (acquired). It is a connective tissue disorder characterized by skin that is loose (lax), hanging, wrinkled, and lacking in elasticity (hyperelasticity). The affected areas of skin may be thickened and dark. In addition, the joints are loose (hypermobility) because of lax ligaments and tendons. The disorder involves a variety of symptoms and signs that result from defects in connective tissue. Defective connective tissue may cause problems in the vocal cords, bones, cartilage, blood vessels, bladder, kidney, digestive system, and lungs.
Four separate inherited forms of this disorder have been identified. Most cases are inherited as one or another of two types of autosomal recessive inheritance. However, cases of autosomal dominant inheritance have been reported, as well as a form that is credited to X-linked inheritance.
American Autoimmune Related Diseases Association, Inc.
22100 Gratiot Ave.
Eastpointe, MI 48021
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
One AMS Circle
Bethesda, MD 20892-3675
Cutis Laxa Internationale
122 Clos des Ecoliers
Saint Cergues, 74140
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
PO Box 241956
Los Angeles, CA 90024