Skin Problems & Treatments Health Center

Generalized rash

A generalized rash is widespread, covers most of the body, or is found on several parts of the body. It may appear in the same place on both hands, feet, arms, or legs.

Many generalized rashes are caused by minor problems, such as dry skin or contact dermatitis, and occur after contact with soap, detergent, or fabric. Many generalized rashes will go away with home treatment.

A generalized rash may be a symptom of a chronic skin disease, such as eczema or psoriasis.

Generalized rashes that are caused by a serious condition rarely appear without other symptoms, such as pain or fever. It is important to determine whether other symptoms are present and to evaluate those symptoms.

Toxic epidermal necrolysis (TEN) is a rare but serious disease that causes a generalized red rash. The skin involved in the rash may peel away, leaving extensive areas that weep or ooze fluid, similar to a severe burn. Medications are the most common cause of TEN.

Toxic shock syndrome (TSS) is an extremely rare condition. An important symptom of TSS is a sunburnlike rash that develops within 2 days of the beginning of a fever 102F or higher. Other symptoms may include a headache, muscle aches, sore throat, vomiting, diarrhea, stomach cramps, profound weakness, confusion, and signs of shock.

See your health professional if you have a generalized rash that has not improved after 2 weeks of home treatment.