Psoriasis

Psoriasis is a common skin disorder that forms thick, red, bumpy patches covered with silvery scales. They can pop up anywhere, but most appear on the scalp, elbows, knees, and lower back.

Psoriasis can't be passed from person to person. It does sometimes happen in members of the same family.

It usually appears in early adulthood. For most people, it affects just a few areas. In severe cases, it can cover large parts of the body. The rashes can heal and then come back throughout a person's life.

Symptoms

Psoriasis starts as small, red bumps, which grow bigger and form scales. The skin appears thick but may bleed easily if you pick or rub off the scales.

Rashes may itch and skin may become cracked and painful . Nails may form pits, thicken, crack and become loose.

How Do I Know If I Have Psoriasis?

If you have a rash that isn’t healing, see your doctor.

Causes

No one knows the exact cause of psoriasis, but experts believe that it’s a combination of things. Something wrong with the immune system causes inflammation, triggering new skin cells to form too quickly. Normally, skin cells are replaced every 10 to 30 days. With psoriasis, new cells grow every 3 to 4 days. The buildup of old cells being replaced by new ones creates those silver scales.

Some things that can trigger outbreaks are:

  • Cuts, scrapes, or surgery
  • Emotional stress
  • Strep infections

Treatment

Luckily, there are many treatments. Some slow the growth of new skin cells, and others relieve itching and dry skin. Your doctor will select a treatment plan that is right for you based on the size of your rash, where it is on your body, your age, your overall health, and other things. Common treatments include:

Treatments for moderate to severe cases of psoriasis include:

  • Light therapy. A doctor uses ultraviolet light to slow the growth of skin cells. PUVA is a treatment that combines a medicine called psoralen with a special form of ultraviolet light.
  • Methotrexate. This drug can cause liver disease and lung problems, so it’s only for serious cases. Doctors closely watch patients. You may have to get lab work, a chest X-ray and possibly a liver biopsy.
  • Retinoids. These pills, creams, and gels are a class of drugs related to Vitamin A. Retinoids can cause serious side effects, including birth defects, so they’re not recommended for women who are pregnant or planning to have children.
  • Cyclosporine. This drug, made to suppress the immune system, may be taken for serious cases that do not respond to other treatments. It can damage the kidneys and raise blood pressure though, so your doctor will closely watch your heath while you take it.
  • Biologic treatments. These work by blocking the body's immune system (which is over-active in psoriasis) to better control the systemic inflammation associated with psoriasis. Biologic medications include adalimumab (Humira), adalimumab-atto (Amjevita), a biosimilar to Humira, etanercept (Enbrel), etanercept-szzs (Erelzi), a biosimilar to Enbrel, infliximab (Remicade), ixekizumab (Taltz), secukinumab (Cosentyx), and ustekinumab (Stelara).
  • Enzyme Inhibitor. The medication apremilast (Otezla) is a new kind of drug for long-term inflammatory diseases like psoriasis and psoriatic arthritis. It's a pill that works by blocking a specific enzyme, which helps to slow other reactions that lead to inflammation.

 

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Is There a Cure?

There’s no cure, but treatment greatly reduces symptoms, even in serious cases. Recent studies have suggested that when you better control the inflammation of psoriasis, the risk of heart disease, stroke, metabolic syndrome, and other diseases associated with inflammation also decrease.

WebMD Medical Reference Reviewed by Stephanie S. Gardner, MD on December 05, 2016

Sources

SOURCES:

FDA. "FDA approves new psoriasis drug Taltz." “FDA approves Amjevita, a biosimilar to Humira.”

National Psoriasis Foundation.

PubMed Health: "Psoriasis."

 

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