Trachyonychia (twenty nail dystrophy of childhood). Any skin disease that affects the nail matrix may result in an abnormal nail plate. There are children, though, who only manifest dystrophy of the nail without any other cutaneous lesions, a condition that has been termed twenty nail dystrophy of childhood. The nails have a rough, sandpaper-like quality as well as longitudinal ridging and occasional splitting at the distal nail edge. Similar nail changes can be seen in lichen planus and alopecia areata. In many patients the condition spontaneously regresses.
Vascular malformations. These are congenital malformations that consist of capillary, venous, arterial, or lymphatic abnormalities. There are often combined alformations that comprise different types of vessels. Examples of vascular malformations include port-wine stains (capillary malformation), cystic hygroma (lymphatic malformation), and venous malformations. Vascular malformations are present at birth and grow proportionately with the child. Some vascular malformations may not manifest themselves until adolescence or adulthood. These figures represent venous malformations on the hand and foot.
Transient neonatal pustular melanosis. This is a benign neonatal dermatosis that is most common among African- American infants. The original lesion is a vesiculopustule, which may be present at birth. This small blister quickly ruptures and leaves a typical collarette of superficial scale processes. Tzanck smear of a pustule of erythema toxicum neonatorum will reveal numerous eosinophils but no multinucleated giant cells or bacteria. Occasionally, peripheral eosinophilia is also present. The cause of this condition is not known, and it resolves spontaneously within 10 days. No treatment is required.
Varicella-zoster virus infection: herpes zoster in T8 to T10 dermatomes. Typical grouped vesicles and pustules with erythema and edema of three contiguous thoracic dermatomes on the posterior chest wall.
Systemic lupus erythematosus. Image illustrates cutaneous involvement of systemic lupus erythematosus (SLE) in the classic butterfly pattern on the face. This macular and intensely erythematous eruption is frequently aggravated by sun exposure and may flare with other symptoms of systemic disease.