Transient neonatal pustular melanosis. This is a benign neonatal dermatosis that is most common among African- American infants. The original lesion is a vesiculopustule, which may be present at birth. This small blister quickly ruptures and leaves a typical collarette of superficial scale processes. Tzanck smear of a pustule of erythema toxicum neonatorum will reveal numerous eosinophils but no multinucleated giant cells or bacteria. Occasionally, peripheral eosinophilia is also present. The cause of this condition is not known, and it resolves spontaneously within 10 days. No treatment is required.
Varicella Chickenpox. Varicella Chickenpox is caused by a virus of the herpes group. The disease is highly contagious and is spread by droplet or direct contact. The incubation period for chickenpox ranges from 11 to 21 days. Prodromal symptoms consist of low-grade fever, headache, anorexia, and malaise. On the following day, the characteristic rash begins to appear. The lesions evolve from erythematous macules to form small papules. Quickly, a clear vesicle arises on this erythematous base. The classic lesion of chickenpox has been poetically described as a “dewdrop on a rose petal.” Over the next several days, the vesicles rupture and then crust. The rash begins on the chest and back and spreads centrifugally to involve the face, scalp, and the extremities. New lesions of chickenpox arise in crops over a period of several days.