The eruption shown was unusual in that it was so widespread and
vesiculopustular. Occasionally, this unimportant eruption must be
differentiated from more serious infectious processes, such as neonatal herpes
simplex. Tzanck smear of a pustule of erythema toxicum neonatorum will reveal
numerous eosinophils but no multinucleated giant cells or bacteria.
Occasionally, peripheral eosinophilia is also present. The cause of this
condition is not known, and it resolves spontaneously within 10 days. No
treatment is required.
Color Atlas of Pediatric
Samuel Weinberg, Neil S. Prose, Leonard Kristal
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