Gingival hyperplasia from phenytoin. The mechanisms of adverse reactions to
drugs vary. Some, like the urticarial or eczematous, are clearly based on an
allergic or immunologic mechanism; others are utterly obscure in mechanism.
Such is the gingival hyperplasia caused by phenytoin. Since it occurs in almost
all patients receiving the drug, all one can say is that the effect probably is
within the normal pharmacologic action of the drug.
Color Atlas of Pediatric
Samuel Weinberg, Neil S. Prose, Leonard Kristal
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