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Nail-Patella Syndrome

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Nail-patella syndrome. This entity, also known as hereditary osteo-onychodysplasia, is a genetic disease linked to a mutation in the gene encoding transcription factor LMX1B, mapped on the long arm of chromosome 9 (9q34). The manifestations include fingernail dysplasia, absent or hypoplastic patellae, the presence of posterior conical iliac horns, and abnormalities of the radial heads. Patients are also at risk for kidney disease and glaucoma.

Color Atlas of Pediatric Dermatology

Samuel Weinberg, Neil S. Prose, Leonard Kristal

Copyright 2008, 1998, 1990, 1975, by the McGraw-Hill Companies, Inc. All rights reserved.

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WebMD Image Collection Reviewed by Varnada Karriem-Norwood, MD on November 10, 2014

Sources

Sources: Color Atlas of Pediatric Dermatology

Samuel Weinberg, Neil S. Prose, Leonard Kristal

Copyright 2008, 1998, 1990, 1975, by the McGraw-Hill Companies, Inc. All rights reserved.

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