"Because psoriasis is a chronic disease, topical products that are safe for extended use must fit within overall, long-term treatment regimens," says Mount Sinai School of Medicine dermatologist Mark Lebwohl, MD, in a news release. "A safe, effective, long-term therapy is critical to improve overall outcomes for these patients."
Side effects of Vectical include changes in the way the body uses calcium. People with known or suspected disturbances in calciummetabolism are warned to use Vectical with caution. That warning also goes for people taking drugs, such as thiazide diuretics, that affect calcium levels.
Caution is also advised for patients taking calcium or vitamin Dsupplements. And while using Vectical, patients are warned against "excessive exposure" to natural or artificial sunlight. The product has not yet been tested in pregnant or nursing women.
How well does Vertical work?
In two eight-week studies of more than 800 psoriasis patients with mild-to-moderate psoriasis, about a third of patients had either psoriasis plaque clearing or minimal psoriasis symptoms. Similar relief was seen by only about a fifth of patients treated with the ointment base lacking the active calcitriol ingredient.