Sleep Disorders Health Center
Diagnosing Periodic Limb Movement Disorder
Exams and Tests
In most people with PLMD, poor sleep and daytime sleepiness are the most
bothersome symptoms. Many people do not link their sleep problem with leg
movements. Sleep disturbance has many, many different causes. Depending on
how you describe your symptoms, your health care provider may ask you many very
detailed questions. These questions concern your medical problems now and in
the past, family medical problems, medications you take, your work and travel
history, and your habits and lifestyle. A detailed physical examination will
look for signs of an underlying cause for your sleep problem.
There is no lab test or imaging study that can prove that you have PLMD.
However, certain tests can identify underlying medical causes such as anemia,
other deficiencies, and metabolic disorders that could cause PLMD.
- You may have blood drawn to check your blood cell counts and hemoglobin,
basic organ functions, chemistry, and thyroid hormone levels. You also may be
checked for certain infections that could cause secondary PLMD.
- A urine sample may be collected to check for traces of drugs that can cause sleep problems.
Polysomnography (sleep lab testing) is the only way to confirm that you have PLMD. As you sleep in the lab, your leg movements can be documented.
At any time during your evaluation, your health care provider may refer you to a neurologist (a specialist in disorders of the nervous system). This specialist can help rule out other neurological problems and confirm the diagnosis of PLMD.
TOPAMAX is approved for migraine prevention in adults only.
TOPAMAX is not used to stop a migraine after it starts.
IMPORTANT SAFETY INFORMATION
Serious risks associated with TOPAMAX include lowered bicarbonate levels in the blood resulting in an increase in the acidity of the blood (metabolic acidosis). Symptoms could include hyperventilation (rapid, deep breathing), tiredness, loss of appetite, irregular heartbeat or changes in the level of alertness. Call your doctor immediately if you get these symptoms. Your doctor may want to do simple blood tests. Chronic, untreated metabolic acidosis may increase the risk for kidney stones or bone disease.
Other serious risks include decreased sweating, increased body temperature, kidney stones, sleepiness, dizziness, confusion, difficulty concentrating, and increased eye pressure (glaucoma). Call your doctor immediately if you have any decrease in vision or eye pain. These problems can lead to blindness if not treated right away.
More common side effects are tingling in arms and legs, loss of appetite, tiredness, nausea, diarrhea, taste change and weight loss.
Tell your doctor about other medications you take. Please see full U.S. Prescribing Information.
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