Sleep Disorders Health Center
Narcolepsy Symptoms
Narcolepsy Overview
Narcolepsy is a sleep disorder that causes overwhelming and severe daytime sleepiness that often occurs at inappropriate times and places. The daytime sleep attacks may occur with or without warning, and can occur repeatedly in a single day. Persons with narcolepsy often have fragmented nighttime sleep with frequent brief awakenings.
Narcolepsy is typically characterized by the following 4 symptoms with varying frequencies:
- Excessive daytime sleepiness (90%)
- Cataplexy (sudden and temporary loss of muscle tone often triggered by
emotions such as laughter) (75%)
- Hallucinations (vivid dreamlike experiences that occur while
falling asleep or upon awakening) (30%)
- Sleep paralysis (paralysis that occurs most often upon falling asleep or waking up; the person is unable to move for a few minutes) (25%)
Less frequently persons have all four symptoms (15%).
The following are some little known facts about narcolepsy:
- Frequently, narcolepsy is unrecognized for many years. There could be a
delay of 10 years between the onset of the condition and the diagnosis.
- Approximately 50% of adults with narcolepsy retrospectively report symptoms
beginning in their teenage years. For most patients, narcolepsy begins between
the ages of 15 and 30 years. It less frequently occurs in children younger
than age 10 years (6%).
- Narcolepsy may lead to impairment of social and academic performance in
otherwise intellectually normal children.
- Narcolepsy is a treatable condition. A multi-modal approach is most effective (medications, a regular nighttime sleep schedule, and scheduled naps during the day) is required for the most favorable outcome.
TOPAMAX is approved for migraine prevention in adults only.
TOPAMAX is not used to stop a migraine after it starts.
IMPORTANT SAFETY INFORMATION
Serious risks associated with TOPAMAX include lowered bicarbonate levels in the blood resulting in an increase in the acidity of the blood (metabolic acidosis). Symptoms could include hyperventilation (rapid, deep breathing), tiredness, loss of appetite, irregular heartbeat or changes in the level of alertness. Call your doctor immediately if you get these symptoms. Your doctor may want to do simple blood tests. Chronic, untreated metabolic acidosis may increase the risk for kidney stones or bone disease.
Other serious risks include decreased sweating, increased body temperature, kidney stones, sleepiness, dizziness, confusion, difficulty concentrating, and increased eye pressure (glaucoma). Call your doctor immediately if you have any decrease in vision or eye pain. These problems can lead to blindness if not treated right away.
More common side effects are tingling in arms and legs, loss of appetite, tiredness, nausea, diarrhea, taste change and weight loss.
Tell your doctor about other medications you take. Please see full U.S. Prescribing Information.
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