Gene Cuts Need for Sleep
People With Rare Gene Mutation Refreshed by 6-Hour Sleep
A Drug for Less Sleep?
So what would happen if someone made a drug that did exactly the same thing
as the DEC2 mutation?
"If I had a drug that gave a similar effect as DEC2, it is possible it would
be pretty safe because the humans who carry it are safe with the mutation," Fu
Tafti notes that before anyone tries to make a DEC2-like drug, future
research will identify more proteins that affect sleep need.
"Then probably we can act on this pathway and increase sleep or reduce
sleep, or make sleep more intense, or improve recovery from sleep deprivation.
But that will be for the next decades, not this one," he says.
The Fu study, and an editorial by Tafti and colleague Hyun Hor, MD, appear
in the Aug. 14 issue of the journal Science.