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How to Stop a Stroke From Striking

WebMD Health News

Feb. 26, 2001 -- What sets off a stroke? Some surprisingly routine things, apparently. According to a preliminary study of stroke triggers, such commonplace activities as drinking alcohol, lifting a large box, and indulging in a vigorous romp in the hay have been tied to the onset of small "ischemic" strokes -- the kind caused by a clot that blocks blood flow in an artery to the brain.

Results from the Stroke Onset Pilot Study were presented at the American Heart Association's 26th International Stroke Conference, held recently in Fort Lauderdale, Fla. At the same meeting, another group of researchers reported that high blood pressure -- known to be a huge risk factor for stroke in people who have had a previous stroke -- remains largely uncontrolled in those seriously at-risk patients.

While many studies have identified risk factors for stroke -- such as high blood pressure and high cholesterol -- "we don't have very good information about what immediately precipitates the stroke itself, what behaviors trigger it at that moment," says Murray Mittleman, MD, lead investigator of the Stroke Onset Pilot Study and director of cardiovascular epidemiology at Beth Israel Deaconess Medical Center in Boston.

"Understanding the patterns in these triggers will hopefully tell researchers more about the underlying biological mechanisms that lead to a stroke," Mittleman tells WebMD. "From this new information, we can hopefully develop novel preventive measures."

For the study, Mittleman and his colleagues recruited 50 patients who had been hospitalized for ischemic strokes. One-third of the participants were women, and the average age was just over 62 years.

Each person was interviewed within two or three days after having their stroke, to pinpoint whether there were patterns in their habits in the days, weeks, and months before their stroke. Specifically, they were asked what medications they were taking, if they were drinking caffeinated beverages or alcohol, or if they were smoking or taking illicit drugs, including marijuana and cocaine.

Researchers also asked about times when people had meals (especially unusually large meals), whether they had strained to go to the bathroom, had sexual intercourse, exerted themselves physically (like lifting a large object), or become angry, anxious, or depressed.

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