Aug. 14, 2008 -- We know that being overweight or obese can contribute to heart
disease and heart attacks, but does extra weight around your belly increase your risk of
A new study says that may be the case.
Led by Yaroslav Winter, MD, researchers from the University of Heidelberg
looked at whether people who were obese or overweight had a greater stroke risk
than those who were normal weight. Researchers zoned in specifically on
There were 1,137 German adults in the study; 379 of those were stroke
patients, and 758 comprised a control group matched for age, gender, and place
of residence. The stroke group included 141 women and 238 men, with an average
age of 67.
Of the stroke group, 301 had suffered a full-blown stroke, 37 had bleeding
in the brain, and 41 experienced what is often called a "mini-stroke" or transient ischemic attack (TIA). A TIA occurs when
blood flow to the brain is temporarily blocked and then is spontaneously
restored. It's often a precursor to a full stroke and is considered a warning
Obesity was measured using some of the following parameters:
Waist circumference (measured at the level of the belly button).
mass index (or BMI, defined as body weight in kilograms divided by height
in meters squared). A BMI of 30 or greater is considered obese.
Waist-hip ratio (or WHR, defined as waist circumference divided by hip
circumference). An abnormal WHR for women is defined as anything greater than
or equal to 0.85. For men, an abnormal WHR is anything greater than or equal to
Obesity was more common in individuals who had suffered a stroke or TIA,
affecting 30% of this group. The BMI, however, was not independently associated
with an increased risk of stroke.
The risk association for waist measurements was far more powerful. People
with bigger waist circumferences (greater than 40 inches for men and 35 inches
for women) had four times the stroke risk when compared with people with
typical waistlines. Participants with the highest WHR had nearly eight times
the risk of stroke when compared to people with the lowest ratios. These
striking results were noted even after adjusting for other risks, like whether
participants were inactive, smoked, or had diabetes.