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NAMENDA XR® (memantine hydrochloride) extended-release capsules are approved for the treatment of moderate to severe Alzheimer's disease. NAMENDA XR is available by prescription only.

NAMENDA XR® Dosing Information

What If My Loved One Is Already Taking NAMENDA® (memantine hydrochloride) Twice a Day?

If your loved one is currently taking twice-a-day NAMENDA, talk to your healthcare provider about how to switch to once-a-day NAMENDA XR® (memantine hydrochloride). Most patients already taking NAMENDA tablets twice a day can start taking NAMENDA XR capsules (the extended-release form), once a day, the very next day.

What If My Loved One Has Never Taken NAMENDA?

The healthcare provider may prescribe or provide you with the NAMENDA XR Titration Pack. It contains a 4-week supply of color-coded NAMENDA XR capsules (7 mg, 14 mg, 21 mg, and 28 mg) to be sure that your loved one is taking the right dose while getting started.

If your loved one is not currently taking NAMENDA twice a day, it's recommended to start NAMENDA XR according to the following schedule:

Note: Actual size of pills is smaller than shown.

The patient should stay on the same dose for at least 7 days. The dose should be increased only if the previous dose was well tolerated.

For patients with severe renal impairment, 14 mg once a day is the recommended dose.

NAMENDA XR should be taken every day. It can be taken with or without food at any time of the day.
NAMENDA XR capsules should be swallowed whole. They should not be divided, crushed, or chewed.
NAMENDA XR must be taken as prescribed by the healthcare provider.

Please see Important Risk Information below and the full Prescribing Information, including Patient Information.

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Important Risk Information

Who should NOT take NAMENDA XR?

NAMENDA XR should not be taken by anyone who is allergic (hypersensitive) to memantine, the active substance in NAMENDA XR, or who has had a bad reaction to NAMENDA XR or any of its ingredients.

What should be discussed with the healthcare provider before taking NAMENDA XR?

Before starting NAMENDA XR, talk to the healthcare provider about all of the patient's past and present medical conditions, including:

  • Seizure disorders
  • Difficulty passing urine
  • Liver or kidney problems

If the patient is taking other medications (including those without a prescription), ask the healthcare provider if NAMENDA XR is right for the patient.

  • Certain medications, changes in diet, or medical conditions may affect the amount of NAMENDA XR in the body and possibly increase side effects.

What are the possible side effects of NAMENDA XR?

The most common side effects associated with NAMENDA XR treatment are headache, diarrhea, and dizziness. This is not a complete list of side effects.

Please see full Prescribing Information, including Patient Information.

WebMD does not endorse any specific product, service, or treatment.

Important Risk Information

Who should NOT take NAMENDA XR?

NAMENDA XR should not be taken by anyone who is allergic (hypersensitive) to memantine, the active substance in NAMENDA XR, or who has had a bad reaction to NAMENDA XR or any of its ingredients.

What should be discussed with the healthcare provider before taking NAMENDA XR?

Before starting NAMENDA XR, talk to the healthcare provider about all of the patient's past and present medical conditions, including:

  • Seizure disorders
  • Difficulty passing urine
  • Liver or kidney problems

If the patient is taking other medications (including those without a prescription), ask the healthcare provider if NAMENDA XR is right for the patient.

  • Certain medications, changes in diet, or medical conditions may affect the amount of NAMENDA XR in the body and possibly increase side effects.

What are the possible side effects of NAMENDA XR?

The most common side effects associated with NAMENDA XR treatment are headache, diarrhea, and dizziness. This is not a complete list of side effects.

Please see full Prescribing Information, including Patient Information.

Be Prepared for the Next Doctor Visit