Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Incontinence & Overactive Bladder Health Center

Font Size

New Overactive Bladder Drug Approved

Enablex Gets FDA Nod to Help Reduce Incontinence
WebMD Health News

Dec. 22, 2004 -- The FDA today approved Enablex for the treatment of overactive bladder, according to the drug's manufacturer.

Novartis Pharmaceuticals, the East Hanover, N.J., affiliate of Swiss drug giant Novartis AG, says the drug should hit the U.S. market in early 2005.

The drug is approved for the treatment of overactive bladder with symptoms of urinary urge incontinence. Urge incontinence is a sudden, uncontrollable urge to urinate. In clinical trials, the drug decreased weekly urinary incontinence episodes by up to 83%. The results were seen within two weeks.

Enablex works by blocking a chemical messenger that makes the bladder muscle contract.

In clinical trials, the most common side effects of Enablex were dry mouth and constipation. Most side effects were mild or moderate and happened during the first two weeks of treatment. Most patients who had these side effects did not have to discontinue treatment.

Some people should not take Enablex: those with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma. People at risk of these conditions should also avoid the drug.

According to a Novartis news release, some 33 million Americans suffer from overactive bladder.

"Millions of patients and their families can be profoundly affected by overactive bladder," Nancy Muller, executive director of the National Association for Continence, says in the news release. "It is important that we continue to advance technology to bring new options to people with overactive bladder to help them manage this condition."

Today on WebMD

Incontinence Women Slideshow
leaking faucet
Public restroom door sign
nachos and beer
woman holding water
Food That Makes You Gotta Go
Male Incontinence Slideshow
Mature woman standing among peers
Worried in bed
woman standing in front of restroom sign
various pills
sitting in chair