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Incontinence & Overactive Bladder Health Center

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Botox Eases Overactive Bladder, 2 Studies Find

Skin smoother brought relief for majority -- but not all -- of patients who got injections for urinary incontinence


On the other hand, a third study slated for the meeting had results that were not that promising. The researchers looked at about 300 patients who had an initial Botox injection to treat incontinence between 2010 and 2014 to determine the treatment's impact on acute urinary retention.

All of the patients had been diagnosed with a form of incontinence for which no specific underlying cause could be identified.

That research team, led by Dr. Olufenwa Milhouse, an urologist in Woodbury, Minn., found that a fifth of the patients ultimately needed catheterization for acute urinary retention. But, the study authors added, 40 percent of patients chose to have a second Botox injection.

Overall, Dr. Michael Chancellor, director of the Aikens Neurourology Research Center at the Beaumont Health System in Royal Oak, Mich., said the message is clear: "Botox is not just for wrinkles anymore."

"I think the two large trials clearly demonstrate that [Botox] has good sustained efficacy and safety after several years of repeated injection," he said.

"Patients who suffer from overactive bladder [urinary incontinence] now have a minimally invasive treatment option, giving them the successful results they want with minimal side effects," Chancellor added.

Botox was first approved by the U.S. Food and Drug Administration to treat overactive bladder in January 2013.

Research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed medical journal.

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