Tribulus terrestris is a fruit-producing Mediterranean plant that's covered with spines. It is also called puncture vine.
People use the fruit, leaf, or root of the tribulus plant as medicine. Some formulations also include other ingredients.
The FDA has approved DMSO as a prescription medication for treating symptoms of painful bladder syndrome. It's also used under medical supervision to treat several other conditions, including shingles.
DMSO is easily absorbed by the skin. It's sometimes used to increase the body's absorption of other medications.
DMSO is available without a prescription most often in gel or cream form. It can be purchased in health food stores, by mail order, and on the Internet.
While it can sometimes be found as an oral supplement, its safety is unclear. DMSO is primarily used by applying it to the skin.
Scleroderma (disease that causes scar tissue to form in the skin)
Other than its use as a prescription medicine, there is little or no scientific evidence to support other claims made about DMSO's effectiveness.
The American Cancer Society says there is no evidence to support the use of DMSO to treat cancer. Using it that way could cause serious delays in getting proper and effective treatment.
A recent analysis of studies on the use of DMSO to relieve osteoarthritis pain found that it was not significantly more effective than placebo in relieving joint pain.
There are no studies that provide guidelines for determining the proper dose of DMSO. The gel used to treat osteoarthritis typically has a concentration of 25%. It is applied three or four times a day. But DMSO sold without a prescription can range from 10% concentration to 90%.