Pycnogenol is a compound of natural chemicals. It comes from the bark of a European pine tree.
Pycnogenol is thought to be an antioxidant that helps protect cells from damage.
Pycnogenol is the registered trademark name for a French formula. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark.
A study in men also suggests that glucosamine sulfate may help a person bend and flex the knee better after a sudden knee injury.
Optimal doses of glucosamine sulfate have not been established. Supplement ingredients and quality may vary widely from maker to maker. This makes it hard to establish a standard dose.
The dose used in many studies to treat knee osteoarthritis was 500 milligrams, taken three times a day.
There are different forms of glucosamine. Check the supplement's ingredients. Some may contain glucosamine sulfate. Other supplements may have glucosamine hydrochloride or another type. Most studies have used glucosamine sulfate.
Glucosamine is sometimes found in skin creams used to treat arthritis pain. There is no proof that glucosamine can move through your skin. Scientists think the pain relief may be due to other ingredients in the cream.
Studies done in a laboratory dish hint that glucosamine sulfate may help fight HIV, the virus that causes AIDS. Much more comprehensive research is needed before scientists can say whether or not this supplement could be helpful for those with the virus.