GABA is a neurotransmitter that blocks impulses between nerve cells in the brain. Low levels of GABA may be linked to:
Anxiety or mood disorders
Researchers suspect that GABA may boost mood or have a calming, relaxing effect on the nervous system.
The evidence to support taking MSM for most of these is lacking.
However, there is evidence that MSM may help a bit with the pain and swelling of kneeosteoarthritis. Also, early animal research shows some promise for decreasing joint degeneration.
Limited small studies also show that MSM may help with exercise recovery. But researchers have more work to do to confirm this.
MSM has shown some effectiveness for treating allergies, repetitive stress injuries, certain bladder disorders like intestinal cystitis, and wounds.
People usually take from 500 milligrams of MSM three times daily to 3 grams twice daily for osteoarthritis. However, optimal doses of MSM have not been set for any condition. And quality and active ingredients in supplements may vary widely from maker to maker. This makes it hard to set a standard dose.
Can you get MSM naturally from foods
Very small amounts of MSM can be found in:
Tea and coffee
But the amounts in these foods are a small fraction of the amount in supplements.