Skip to content
My WebMD Sign In, Sign Up
Font Size

Overall Level of Evidence for Coenzyme Q10

To assist readers in evaluating the results of human studies of complementary and alternative medicine (CAM) treatments for cancer, the strength of the evidence (i.e., the "levels of evidence") associated with each type of treatment is provided whenever possible. To qualify for a level of evidence analysis, a study must:

  • Be published in a peer-reviewed scientific journal.
  • Report on a therapeuticoutcome or outcomes, such as tumorresponse, improvement in survival, or measured improvement in quality of life.
  • Describe clinical findings in sufficient detail that a meaningful evaluation can be made.

Separate levels of evidence scores are assigned to qualifying human studies on the basis of statistical strength of the study design and scientific strength of the treatment outcomes (i.e., endpoints) measured. The resulting two scores are then combined to produce an overall score. A table showing the levels of evidence scores for qualifying human studies cited in this summary is presented below. For an explanation of the scores and additional information about levels of evidence analysis of CAM treatments for cancer, refer to Levels of Evidence for Human Studies of Cancer Complementary and Alternative Medicine.

Coenzyme Q10 Summary: Reference Numbers and the Corresponding Levels of Evidence

Reference Number Statistical Strength of Study Design Strength of Endpoints Measured Combined Score
[1]3iii ­ Nonconsecutive case series Diii ­ Indirect surrogates -- tumor response rate 3iiiDiii

References:

  1. Lockwood K, Moesgaard S, Hanioka T, et al.: Apparent partial remission of breast cancer in 'high risk' patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Mol Aspects Med 15 (Suppl): s231-40, 1994.
1

WebMD Public Information from the National Cancer Institute

Last Updated: October 07, 2011

Vitamins and
Supplements
Lifestyle Guide

Which Nutrients
Are You Missing?

Learn More

Today on WebMD

Woman taking a vitamin or supplement
Article
Man taking a vitamin or supplement
Article
 
clams
Quiz
Woman in sun
Slideshow
 
Couple in bed
Article
!!69X75_Vitamins_Supplements.jpg
Evaluator
 
Woman sleeping
Article
Woman staring into space with coffee
Article
 
Related Newsletters

Stay Informed with the latest must-read information delivered right to your inbox.