Tribulus Terrestris

Medically Reviewed by Melinda Ratini, MS, DO on September 12, 2023
Written by Annie Stuart
2 min read

Tribulus terrestris is a fruit-producing Mediterranean plant that's covered with spines. It is also called puncture vine.

People use the fruit, leaf, or root of the tribulus plant as medicine. Some formulations also include other ingredients.

Over the years, people have taken tribulus in an attempt to enhance athletic performance, body building, and for a wide range of health issues that may include heart and circulatory conditions and sexual issues.

But does it work? Limited studies suggest it might be helpful in lessening symptoms of angina and in enhancing athletic performance. There have also been some studies that show some benefit to people with certain sexual problems and to those suffering from infertility. More research is needed.

Evidence is lacking that shows benefits of tribulus for other health conditions.

With a lack of research to draw on, it's not clear what a safe dosage is. Also, quality and active ingredients in supplements may vary widely from maker to maker. This makes it difficult to set a standard dose.

Yes. The spine-covered fruit should be eaten with caution.

 

Side effects. Taking tribulus as a supplement for a short time is probably safe, provided that you're healthy and you are not pregnant or breastfeeding. Side effects can include trouble sleeping, an upset stomach, and irregular periods.

Risks. Lab tests on animals link tribulus to problems in fetal development. So stay away from tribulus if you are pregnant or breastfeeding.

Also, men should be aware that there are some concerns about changes to male hormones that may affect men with prostate cancer.

Interactions. Tribulus may interact with some medicines used to treat diabetes and high blood pressure, as well as some used to prevent blood clots.

But tribulus has been known to interact with certain medications. Do not take if you are taking heart and blood pressure medicines. such as:

If you are taking diabetes medications, tribulus might decrease your blood sugars to dangerously low levels. It may also increase the effect that steroids have on your body.

Be sure to tell your doctor about any you're taking, even if they're natural. That way, your doctor can check on any potential side effects or interactions with medications, foods, or other herbs and supplements. They can let you know if the supplement may be risky for you.

The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. Unlike drug manufacturers, the makers of supplements don’t have to show their products are safe or effective before selling them on the market.