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COD LIVER OIL

Other Names:

Aceite de Higado de Bacalao, Acides Gras Oméga 3, Acides Gras N-3, Acides Gras Polyinsaturés, Cod Oil, Fish Liver Oil, Fish Oil, Halibut Liver Oil, Huile de Foie, Huile de Foie de Flétan, Huile de Foie de Morue, Huile de Foie de Poisson, Huile d...
See All Names

NIACIN AND NIACINAMIDE (VITAMIN B3) Overview
NIACIN AND NIACINAMIDE (VITAMIN B3) Uses
NIACIN AND NIACINAMIDE (VITAMIN B3) Side Effects
NIACIN AND NIACINAMIDE (VITAMIN B3) Interactions
NIACIN AND NIACINAMIDE (VITAMIN B3) Dosing
NIACIN AND NIACINAMIDE (VITAMIN B3) Overview Information

Cod liver oil can be obtained from eating fresh cod liver or by taking supplements.

Cod liver oil is used for high cholesterol, high triglycerides, kidney disease in people with diabetes, high blood pressure, heart disease, osteoarthritis, depression, an autoimmune disease called systemic lupus erythematosus (SLE), glaucoma, and middle ear infections (otitis media).

Some people put cod liver oil on their skin to speed wound healing.

When taken in appropriate doses by mouth, cod liver oil seems to help lower high triglycerides (a type of blood fat), lower high blood pressure, and treat some symptoms of kidney disease related to diabetes. It doesn’t seem to lower high cholesterol or reduce arthritis pain. Other uses are still under investigation.

How does it work?

Cod liver oil contains certain "fatty acids" that prevent the blood from clotting easily. These fatty acids also reduce pain and swelling.

NIACIN AND NIACINAMIDE (VITAMIN B3) Uses & Effectiveness What is this?

Likely Effective for:

  • Lowering blood fats called triglycerides. Taking cod liver oil by mouth can reduce triglyceride levels by 20% to 50% in people with high triglyceride levels.

Possibly Effective for:

  • High blood pressure. Taking cod liver oil by mouth seems to lower blood pressure (both numbers) a small, but important, amount in people with mild high blood pressure.
  • Kidney disease in people with type 2 diabetes. Taking cod liver oil seems to reduce protein in the urine, a marker for kidney disease severity.

Possibly Ineffective for:

  • Osteoarthritis.
  • Cholesterol disease that runs in families (familial hypercholesterolemia).

Insufficient Evidence for:

  • Depression. There is some evidence that people who take cod liver oil have fewer symptoms of depression than other people.
  • Irregular heartbeat in people with heart disease. There is some early evidence that cod liver oil might help to prevent certain types of irregular heartbeat.
  • Ear infections in young children. Preliminary research suggests that taking cod liver oil along with a children's multivitamin-mineral product containing selenium might prevent or decrease the number of ear infections in young children.
  • Heart disease.
  • Systemic lupus erythematosus (SLE).
  • Wound healing.
  • Glaucoma.
  • Other conditions.
More evidence is needed to rate cod liver oil for these uses.


NIACIN AND NIACINAMIDE (VITAMIN B3) Side Effects & Safety

Cod liver oil is LIKELY SAFE for most people. It can cause side effects including belching, bad breath, heartburn, and nosebleeds. Taking cod liver oil with meals can often decrease these side effects.

High doses are POSSIBLY UNSAFE. They might keep blood from clotting and can increase the chance of bleeding. Vitamin A and vitamin D levels might also become too high with high doses of cod liver oil. High doses might also cause nausea and loose stools.

The safety of cod liver oil when used on the skin is unknown.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of cod liver oil during pregnancy and breast-feeding. Stay on the safe side and avoid use.

High blood pressure: Cod liver oil can lower blood pressure and might cause blood pressure to go too low if used along with medications for high blood pressure. Be careful when using cod liver oil if you are taking high blood pressure drugs.

NIACIN AND NIACINAMIDE (VITAMIN B3) Interactions What is this?

Moderate Interaction Be cautious with this combination

  • Medications for high blood pressure (Antihypertensive drugs) interacts with COD LIVER OIL

    Cod liver oil seems to decrease blood pressure. Taking cod liver oil along with medications for high blood pressure might cause your blood pressure to go too low.

    Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

  • Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with COD LIVER OIL

    Cod liver oil might slow blood clotting. Taking cod liver oil along with medications that also slow clotting might increase the chances of bruising and bleeding.

    Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.


NIACIN AND NIACINAMIDE (VITAMIN B3) Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For lowering triglycerides: 20 mL of cod liver oil per day.
  • For high cholesterol: 30 mL of cod liver oil per day.
  • For lowering blood pressure: 20 mL of cod liver oil per day.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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