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FLUORIDE

Other Names:

Acidulated Phosphate Fluoride, Atomic number 9, Calcarea Fluorica, F, Fluorophosphate, Fluorure, Fluorure d’Hydrogène, Fluorure de Phosphate Acidulé, Fluorure de Sodium, Fluorure Stanneux, Fluoruro, Hydrogen Fluoride, Monofluorophosphate,...
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Acidulated Phosphate Fluoride (FLUORIDE) Overview
Acidulated Phosphate Fluoride (FLUORIDE) Uses
Acidulated Phosphate Fluoride (FLUORIDE) Side Effects
Acidulated Phosphate Fluoride (FLUORIDE) Interactions
Acidulated Phosphate Fluoride (FLUORIDE) Dosing
Acidulated Phosphate Fluoride (FLUORIDE) Overview Information

Fluoride is a form of the chemical element fluorine. It is used as medicine.

Fluoride is added to public drinking water to prevent tooth decay. Children who do not drink fluorinated public water because their homes use water from a private well often take fluoride tablets to prevent tooth decay. Fluoride is added to toothpaste and mouthwashes so it can be applied directly to the teeth to prevent tooth decay.

Fluoride is also taken by mouth for treating weakened bones (osteoporosis) and for preventing bone loss in people with rheumatoid arthritis and Crohn's disease.

How does it work?

Fluoride protects teeth from the bacteria in plaque. It also promotes new bone formation. This is different than most medicines used for weak bones (osteoporosis), which fight osteoporosis by keeping bone from being broken down.

Acidulated Phosphate Fluoride (FLUORIDE) Uses & Effectiveness What is this?

Effective for:

  • Preventing tooth decay, when fluoride is added to drinking water or included in toothpastes, mouthwashes, and other dental products.

Possibly Effective for:

  • Treating osteoporosis (bone loss). Fluoride taken by mouth continuously or cyclically (three months on, one month off) might increase bone mineral density, which is an indicator of bone strength. Fluoride seems to work better for improving bone strength in older women when combined with hormone replacement therapy. However, it’s not clear whether taking fluoride actually reduces the chance of weak bones breaking.

Insufficient Evidence for:

  • Preventing bone loss in people with rheumatoid arthritis.
  • Preventing bone loss in people with Crohn's disease (an intestinal disorder).
  • Other conditions.
More evidence is needed to rate the effectiveness of fluoride for these uses.


Acidulated Phosphate Fluoride (FLUORIDE) Side Effects & Safety

Fluoride is safe for most people in the amounts added to public water supplies and used in toothpastes and mouthwashes, and applied by dentists. Low doses (up to 20 mg per day of elemental fluoride) of supplemental fluoride taken by mouth appear to be safe for most people. Higher doses are UNSAFE and can weaken bones and ligaments, and cause muscle weakness and nervous system problems. High doses of fluoride in children before their permanent teeth come through the gums can cause tooth discoloration.

Toothpaste and fluoride rinses should not be swallowed routinely, particularly by children. It’s a good idea to make sure that children under six years of age use only a pea-sized amount of fluoride-containing toothpaste, just in case they swallow some.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Fluoride seems to be safe during pregnancy and breast-feeding when taken in doses below the tolerable upper intake level (UL) of 10 mg per day of elemental fluoride and when applied directly to the teeth in toothpastes and mouthwashes. But higher doses are UNSAFE and can weaken bones and ligaments, and cause muscle weakness and nervous system problems.

Acidulated Phosphate Fluoride (FLUORIDE) Interactions What is this?

We currently have no information for Acidulated Phosphate Fluoride (FLUORIDE) Interactions

Acidulated Phosphate Fluoride (FLUORIDE) Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • To prevent tooth decay (dental caries): in the US, fluoride is added to city water to a concentration of 0.7 to 1.2 parts per million (ppm). To prevent dental caries in areas where the fluoride level in drinking water is less than 0.3 ppm (such as in well water), children 6 months to 3 years should receive a fluoride supplement of 0.25 mg per day; children 3 to 6 years, 0.5 mg per day; and children 6 to 16 years, 1 mg per day. For children living in areas where the fluoride level is 0.3 to 0.6 ppm, children 3 to 6 years should receive 0.25 mg per day, and children 6 to 16 years, 0.5 mg per day. No supplement is needed in areas where the fluoride in drinking water exceeds 0.6 ppm.
  • For treating weak bones (osteoporosis): 15 to 20 mg per day of elemental fluoride.
The daily Adequate Intakes (AI) for elemental fluoride from all sources including drinking water are: infants birth through 6 months, 0.01 mg; babies age 7 through 12 months, 0.5 mg; children 1 through 3 years, 0.7 mg; 4 through 8 years, 1 mg; 9 through 13 years, 2 mg; 14 through 18 years, 3 mg; men 19 years and older, 4 mg; women 14 years and older, including those who are pregnant or breast feeding, 3 mg.

The daily upper intake levels (UL) for fluoride, the highest level at which no harmful effects are expected, are 0.7 mg for infants birth through 6 months; 0.9 mg for infants 7 through 12 months; 1.3 mg for children 1 through 3 years; 2.2 mg for children 4 through 8 years and 10 mg for children older than 8 years, adults, and pregnant and breast feeding women.

Sodium fluoride contains 45% elemental fluoride. Monofluorophosphate contains 19% elemental fluoride.

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