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IDEBENONE

Other Names:

2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone, Hydroxydecyl Benzoquinone, Idebenona, Idébénone.

IDEBENONE Overview
IDEBENONE Uses
IDEBENONE Side Effects
IDEBENONE Interactions
IDEBENONE Dosing
IDEBENONE Overview Information

Idebenone is a man-made product similar to coenzyme Q-10.

Idebenone is used for Alzheimer's disease, liver disease, and heart disease; as well as a number of inherited disorders including Leber's disease (an eye condition), mitochondrial encephalomyopathies (nerve and muscle disorders), and Friedreich's ataxia (a nervous system disorder that worsens over time, producing gait and speech problems, and eventually leading toward heart disease and diabetes).

How does it work?

Idebenone seems to have antioxidant activity, and appears to protect a wide variety of cells from oxidative damage.

IDEBENONE Uses & Effectiveness What is this?

Possibly Effective for:


Insufficient Evidence for:

  • Friedreich's ataxia (an inherited progressive condition affecting the nerves that can lead to heart disease and diabetes). Some developing research suggests that taking idebenone may help control heart damage associated with Friedreich's ataxia. But other research hasn’t shown this benefit. Idebenone does not appear to slow the progression of this condition.
  • Mitochondrial encephalomyopathies (a group of disorders that lead to muscle and nervous system problems). There is some research that suggests that taking idebenone might reduce symptoms in patients with some of these conditions.
  • Other conditions.
More evidence is needed to rate the effectiveness of idebenone for these uses.


IDEBENONE Side Effects & Safety

Idebenone seems safe for most people.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of idebenone during pregnancy and breast-feeding. Stay on the safe side and avoid use.

IDEBENONE Interactions What is this?

We currently have no information for IDEBENONE Interactions

IDEBENONE Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For Alzheimer's disease: 90-120 mg of idebenone three times daily.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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