Skip to content
My WebMD Sign In, Sign Up

Find a Vitamin or Supplement

LIMONENE

Other Names:

Alpha-Limonene, Alpha-Limonène, Dipentene, D-Limonene, D-Limonène, L-Limonene, L-Limonène, Limonène, Limoneno, R-Limonene, R-Limonène, S-Limonene, S-Limonène.

CREATINE Overview
CREATINE Uses
CREATINE Side Effects
CREATINE Interactions
CREATINE Dosing
CREATINE Overview Information

Limonene is a chemical found in the peels of citrus fruits and in other plants. It is used to make medicine.

Limonene is used to promote weight loss, prevent cancer, treat cancer, and treat bronchitis.

In foods, beverages, and chewing gum, limonene is used as a flavoring.

In pharmaceuticals, limonene is added to help medicinal ointments and creams penetrate the skin.

In manufacturing, limonene is used as a fragrance, cleaner (solvent), and as an ingredient in water-free hand cleansers.

How does it work?

Limonene may block cancer-forming chemicals and kill cancer cells in the laboratory. But more research is needed to know if this occurs in humans.

CREATINE Uses & Effectiveness What is this?

Insufficient Evidence for:

  • Cancer treatment. One form of limonene (D-limonene) seems to build up in tumors in people with advanced cancer, when it is taken by mouth in 21-day cycles. The high levels of limonene in the tumors may slow down the progress of the cancer, but their effect on the person’s survival is uncertain.
  • Cancer prevention.
  • Weight loss.
  • Bronchitis.
  • Other conditions.
More evidence is needed to rate the effectiveness of limonene for these uses.


CREATINE Side Effects & Safety

Limonene is safe in food amounts. It also appears to be safe for most people in medicinal amounts when taken by mouth for up to one year.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Limonene is safe in food amounts, but there's not enough information to know if it's safe in larger medicinal amounts. Stay on the safe side and avoid using limonene as a medicine until more is known.

CREATINE Interactions What is this?

Moderate Interaction Be cautious with this combination

  • Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with LIMONENE

    Some medications are changed and broken down by the liver.

    Limonene might increase how quickly the liver breaks down some medications. Taking limonene along with some medications that are changed by the liver can lead to a variety of effects and side effects. Before taking limonene talk to your healthcare provider if you take any medications that are changed by the liver.

    Some of these medications that are changed by the liver include diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), and piroxicam (Feldene), amitriptyline (Elavil), warfarin (Coumadin), glipizide (Glucotrol), losartan (Cozaar), and others.

  • Medications that decrease the break down of other medications by the liver (Cytochrome P450 2C19 (CYP2C19) inhibitors) interacts with LIMONENE

    Limonene might be broken down by the liver. Taking limonene along with medications that decrease the break down of limonene in the liver might increase the effects and side effects of limonene.

    Some medications that might decrease the breakdown of limonene in the liver include cimetidine (Tagamet), fluvoxamine (Luvox), omeprazole (Prilosec); ticlopidine (Ticlid), topiramate (Topamax), and others.

  • Medications that decrease the break down of other medications by the liver (Cytochrome P450 2C9 (CYP2C9) inhibitors) interacts with LIMONENE

    Limonene might be broken down by the liver. Taking limonene along with medications that decrease the break down of limonene in the liver might increase the effects and side effects of limonene.

    Some medications that might decrease the breakdown of limonene in the liver include amiodarone (Cordarone), fluconazole (Diflucan), lovastatin (Mevacor), paroxetine (Paxil), zafirlukast (Accolate), and many others.

  • Medications that increase the break down of other medications by the liver (Cytochrome P450 2C19 (CYP2C19) inducers) interacts with LIMONENE

    Limonene might be broken down by the liver. Taking limonene along with medications that increase the break down of limonene in the liver might decrease the effects of limonene.

    Some medications that might increase the breakdown of limonene in the liver include carbamazepine (Tegretol), prednisone (Deltasone), and rifampin (Rifadin, Rimactane).

  • Medications that increase the break down of other medications by the liver (Cytochrome P450 2C9 (CYP2C9) inducers) interacts with LIMONENE

    Limonene might be broken down by the liver. Taking limonene along with medications that increase the break down of limonene in the liver might decrease the effects of limonene.

    Some medications that might increase the breakdown of limonene in the liver include rifampin (Rifadin, Rimactane) and secobarbital (Seconal).


CREATINE Dosing

The appropriate dose of limonene depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for limonene. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

See 3 Reviews for this Treatment - OR -

Review this Treatment

Learn about User Reviews and read IMPORTANT information about user generated content

Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

Search for a Vitamin or Supplement

Ex. Ginseng, Vitamin C, Depression

Today on WebMD

Woman taking a vitamin or supplement
Article
Man taking a vitamin or supplement
Article
 
clams
Quiz
Woman in sun
Slideshow
 
Flaxseed added fiber
Video
!!69X75_Vitamins_Supplements.jpg
Evaluator
 
Woman sleeping
Article
Woman staring into space with coffee
Article
 
IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.