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HIGENAMINE

Other Names:

1-[(4-Hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol; 1-(p-hydroxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinolin; 1(S)-Norcoclaurine; dl-Demethylcoclaurine; DMC; Higénamine; Higenamine Hydrobromide; Higenamine Hydrochloride; ...
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HIGENAMINE Overview
HIGENAMINE Uses
HIGENAMINE Side Effects
HIGENAMINE Interactions
HIGENAMINE Dosing
HIGENAMINE Overview Information

Higenamine is a chemical found in several plants including aconite, Annona squamosa, Nandina domestica (sacred bamboo), and others.

In supplements, higenamine is now showing up in products promoted as a pre-workout supplement for improving athletic performance. There is also interest in using higenamine for weight loss, cough, asthma, heart failure, and erectile dysfunction.

How does it work?

Higenamine works like a stimulant. In some parts of the body it causes tissues to relax. In other parts of the body, such as the heart, it causes tissue to contract. It seems to increase heart contractions and speed up the heart rate.

HIGENAMINE Uses & Effectiveness What is this?

Insufficient Evidence for:

  • Weight loss.
  • Athletic performance.
  • Cough.
  • Asthma.
  • Breathing disorders.
  • Heart failure.
  • Erectile dysfunction.
  • Other conditions.
More evidence is needed to rate higenamine for these uses.


HIGENAMINE Side Effects & Safety

Higenamine is POSSIBLY UNSAFE when taken by mouth. The purified or extracted chemical higenamine has not been studied in people. Therefore, its safety is not clear. However, higenamine is one of the main chemicals in a plant called aconite. Aconite has been shown to cause serious heart-related side effects including arrhythmias and even death. These side effects from aconite ingestions may, in part, be caused by the higenamine chemical.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough information to know if higenamine is safe during pregnancy and breast feeding. It should be avoided.

Irregular heartbeat (heart arrhythmia): Higenamine might cause a rapid heartbeat. Therefore it could potentially worsen an irregular heartbeat. If you have an irregular heartbeat, do not take higenamine.

Surgery: Higenamine acts like a stimulant, so it might interfere with surgery by increasing heart rate. Stop taking higenamine at least 2 weeks before a scheduled surgery.

HIGENAMINE Interactions What is this?

We currently have no information for HIGENAMINE Interactions

HIGENAMINE Dosing

The appropriate dose of higenamine depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for higenamine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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