Overview

1,3-DMBA is a chemical with stimulant effects that's found in small amounts in some plants. But the 1,3-DMBA found in supplements might be made in a lab.

1,3-DMBA causes blood vessels to contract, which increases blood pressure and speeds up the heart.

People use 1,3-DMBA for athletic performance, memory and thinking skills, obesity, and other conditions, but there is no good scientific evidence to support these uses. 1,3-DMBA might also be unsafe.

The US FDA banned the use of 1,3-DMBA in dietary supplements in 2015, but it's still found in some products. The 1,3-DMBA found in supplements is most likely made in a lab, since plants contain only very small amounts of this chemical. 1,3-DMBA is on the World Anti-Doping Agency's (WADA) prohibited substances list. Don't confuse 1,3-DMBA with 1,3-DMAA, 1,4-DMAA, or Dimethylhexylamine (DMHA). These are not the same.

Uses & Effectiveness ?

We currently have no information for 1,3-DMBA overview.

Side Effects

When taken by mouth: 1,3-DMBA is likely unsafe. It's believed to work like a stimulant, which might increase the chance of serious side effects such as rapid heartbeat, high blood pressure, and increased risk of heart attack or stroke.

Special Precautions and Warnings

When taken by mouth: 1,3-DMBA is likely unsafe. It's believed to work like a stimulant, which might increase the chance of serious side effects such as rapid heartbeat, high blood pressure, and increased risk of heart attack or stroke.

Pregnancy and breast-feeding: 1,3-DMBA is likely unsafe. It's believed to work like a stimulant, which might increase the chance of serious side effects when pregnant or breast-feeding.

Heart conditions: 1,3-DMBA might increase heart rate and blood pressure, which could make heart conditions worse. Do not use 1,3-DMBA if you have a heart condition.

High blood pressure: 1,3-DMBA might increase blood pressure. Do not use 1,3-DMBA if you have high blood pressure.

Glaucoma: 1,3-DMBA might make glaucoma worse. Do not use 1,3-DMBA if you have glaucoma.

Surgery: 1,3-DMBA might increase heart rate and blood pressure, which could interfere with the drugs used during surgery. Stop taking 1,3-DMBA at least 2 weeks before a scheduled surgery.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Stimulant drugs interacts with 1,3-DMBA

    Stimulant drugs, such as amphetamines and cocaine, speed up the nervous system. By speeding up the nervous system, stimulant medications can increase blood pressure and speed up the heartbeat. 1,3-DMBA might also speed up the nervous system. Taking 1,3-DMBA along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure.

    Minor Interaction

    Be watchful with this combination

  • Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with 1,3-DMBA

    Some medications are changed and broken down by the liver. 1,3-DMBA might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Dosing

Despite being banned in the US, 1,3-DMBA is still found in some dietary supplements marketed for athletic performance and weight loss. Some supplements claim that 1,3-DMBA is extracted from pouchong tea or Coreopsis tinctoria, but the amount found in these products is much greater than would be naturally found in plants.

1,3-DMBA is believed to work like a stimulant, which might increase the chance of serious side effects. 1,3-DMBA is also on the World Anti-Doping Agency's (WADA) prohibited substances list.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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