ALBIZIA JULIBRISSIN: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Albizia julibrissin is a tree that was originally grown in southern and eastern Asia. The flowers and stem bark are used to make medicine.

Albizia julibrissin is used for anxiety, cancer, insomnia, skin infections, and other conditions, but there is no good scientific evidence to support its use.

How does it work ?

The chemicals in Albizia julibrissin might have calming, sleep inducing, anticancer, and antioxidant effects.

Uses & Effectiveness ?

Insufficient Evidence for

Anxiety.
Cancer.
Depression.
Insomnia.
Sore throat.
To improve mood.
Trauma.
Insect bites.
Skin infection (boils and abscesses).
Bed sores (pressure ulcers).
Fractures.
Sprains.
Other conditions.

More evidence is needed to rate Albizia julibrissin for these uses.

Side Effects

Special Precautions and Warnings

When taken by mouth: There isn't enough reliable information to know if Albizia julibrissin is safe or what the side effects might be.

When applied to the skin: There isn't enough reliable information to know if Albizia julibrissin is safe or what the side effects might be. Pregnancy and breast-feeding: There isn't enough reliable information to know if Albizia julibrissin is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Surgery: Albizia julibrissin might affect the central nervous system. It might increase the effects of anesthesia and other medications on the brain during and after surgery. Stop taking Albizia julibrissin at least 2 weeks before a scheduled surgery.

Interactions ?

Moderate Interaction

Be cautious with this combination

Sedative medications (CNS depressants) interacts with ALBIZIA JULIBRISSIN
Albizia julibrissin might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking Albizia julibrissin along with sedative medications might cause too much sleepiness.

Some sedative medications include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), clonazepam (Klonopin), lorazepam (Ativan), zolpidem (Ambien), and others.

Dosing

The appropriate dose of Albizia julibrissin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Albizia julibrissin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

Ikeda, T., Fujiwara, S., Araki, K., Kinjo, J., Nohara, T., and Miyoshi, T. Cytotoxic glycosides from Albizia julibrissin. J Nat Prod 1997;60(2):102-107. View abstract.

Jung, M. J., Chung, H. Y., Kang, S. S., Choi, J. H., Bae, K. S., and Choi, J. S. Antioxidant activity from the stem bark of Albizzia julibrissin. Arch Pharm Res 2003;26(6):458-462. View abstract.

Jung, M. J., Kang, S. S., and Choi, J. S. A new (E)4-hydroxy-dodec-2-enedioic acid from the stem bark of Albizzia julibrissin. Arch Pharm Res 2003;26(3):207-209. View abstract.

Jung, M. J., Kang, S. S., Jung, H. A., Kim, G. J., and Choi, J. S. Isolation of flavonoids and a cerebroside from the stem bark of Albizzia julibrissin. Arch Pharm Res 2004;27(6):593-599. View abstract.

Jung, M. J., Kang, S. S., Jung, Y. J., and Choi, J. S. Phenolic glycosides from the stem bark of Albizzia julibrissin. Chem Pharm Bull (Tokyo) 2004;52(12):1501-1503. View abstract.

Kang, T. H., Jeong, S. J., Kim, N. Y., Higuchi, R., and Kim, Y. C. Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz. J Ethnopharmacol 2000;71(1-2):321-323. View abstract.

Li, Z. P., Gao, S., Hao, C. S., and Fan, G. M. [Studies on chemical constituents from the flower of Albizzia julibrissin Durazz]. Zhongguo Zhong Yao Za Zhi 2000;25(2):103-104. View abstract.

Liang, H., Tong, W. Y., Zhao, Y. Y., Cui, J. R., and Tu, G. Z. An antitumor compound julibroside J28 from Albizia julibrissin. Bioorg Med Chem Lett 2005;15(20):4493-4495. View abstract.

Roy, B., Pramanik, K., and Mukhopadhyay, B. Synthesis of a tetra- and a trisaccharide related to an anti-tumor saponin "Julibroside J28" from Albizia julibrissin. Glycoconj J 2008;25(2):157-166. View abstract.

Won, H. J., Han, C. H., Kim, Y. H., Kwon, H. J., Kim, B. W., Choi, J. S., and Kim, K. H. Induction of apoptosis in human acute leukemia Jurkat T cells by Albizzia julibrissin extract is mediated via mitochondria-dependent caspase-3 activation. J Ethnopharmacol 2006;106(3):383-389. View abstract.

Woo WS, Kang SS. Isolation of a new monoterpene conjugated triterpenoid from the stem bark of Albizzia julibrissin. J Nat Prod 1984;47(3):547-9. View abstract.

Xu, T. H., Li, H. T., Xu, Y. J., Zhao, H. F., Xie, S. X., Han, D., Si, Y. S., Li, Y., Niu, J. Z., and Xu, D. M. A new triterpenoid saponin from Albizia julibrissin Durazz. J Asian Nat Prod Res 2008;10(7-8):781-785. View abstract.

Zheng, L., Zheng, J., Wu, L. J., and Zhao, Y. Y. Julibroside J8-induced HeLa cell apoptosis through caspase pathway. J Asian Nat Prod Res 2006;8(5):457-465. View abstract.

Zou, K., Cui, J. R., Wang, B., Zhao, Y. Y., and Zhang, R. Y. A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin. J Asian Nat Prod Res 2005;7(6):783-789. View abstract.

Zou, K., Tong, W. Y., Liang, H., Cui, J. R., Tu, G. Z., Zhao, Y. Y., and Zhang, R. Y. Diastereoisomeric saponins from Albizia julibrissin. Carbohydr Res 2005;340(7):1329-1334. View abstract.

Zou, K., Zhao, Y. Y., and Zhang, R. Y. A cytotoxic saponin from Albizia julibrissin. Chem Pharm Bull (Tokyo) 2006;54(8):1211-1212. View abstract.