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HYDRAZINE SULFATE

Other Names:

Sehydrin, Sulfate d'Hydrazine, Sulfato de Hidracina.

HYDRAZINE SULFATE Overview
HYDRAZINE SULFATE Uses
HYDRAZINE SULFATE Side Effects
HYDRAZINE SULFATE Interactions
HYDRAZINE SULFATE Dosing
HYDRAZINE SULFATE Overview Information

Hydrazine sulfate is a chemical used in industry and as jet fuel. Some people use it as medicine.

Hydrazine sulfate is used for treating colon and rectal (colorectal) cancer, lung cancer, brain cancer (neuroblastoma), Hodgkin's disease (lymph cancer), and other cancers. It is also used for the general weight loss and wasting (cachexia) associated with cancer.

How does it work?

Hydrazine sulfate may block chemical reactions in the body that might lead to malnutrition and muscle wasting associated with cancer.

HYDRAZINE SULFATE Uses & Effectiveness What is this?

Possibly Ineffective for:

  • Colon and rectal cancer that has spread (metastatic colorectal cancer).

Likely Ineffective for:

  • Use with chemotherapy for non-small cell lung cancer. Adding hydrazine sulfate to chemotherapy doesn't significantly improve quality of life, tumor response, weight gain, or survival in people with this type of lung cancer.

Insufficient Evidence for:

  • General weight loss and wasting associated with cancer. Developing research suggests that hydrazine sulfate might slow weight loss in some cancer patients.
  • Cancer. There is some evidence that hydrazine sulfate is ineffective for treating ovarian cancer, colorectal cancer, breast cancer, lung cancer, pancreatic cancer, cervical cancer, prostate cancer, uterine cancer, melanoma, and other kinds of cancer.
  • Hodgkin's disease (lymph cancer). Some research suggests that hydrazine sulfate might slow the progress of advanced Hodgkin's disease.
  • Brain cancer (neuroblastoma). There is some evidence that hydrazine sulfate might prevent the growth of neuroblastoma.
  • Other conditions.
More evidence is needed to rate the effectiveness of hydrazine sulfate for these uses.


HYDRAZINE SULFATE Side Effects & Safety

Hydrazine sulfate is POSSIBLY UNSAFE. It has been linked to cases of liver damage, seizure, coma, and death.

Hydrazine sulfate can cause some side effects including nausea, vomiting, dizziness, drowsiness, nerve problems, violent behavior, restlessness, seizures, coma, confusion, mood stimulation, excitement, weakness, irregular breathing, abnormal blood sugar levels, rash, and kidney damage.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Hydrazine sulfate is POSSIBLY UNSAFE for anyone, including pregnant and breast-feeding women. It has been linked to cases of liver damage, seizure, coma, and death.

Diabetes: Hydrazine sulfate is POSSIBLY UNSAFE for anyone, but especially for people with diabetes. Hydrazine sulfate might interfere with blood sugar control.

Liver disease: Hydrazine sulfate is POSSIBLY UNSAFE for anyone, but especially for people with liver disease. Hydrazine sulfate can damage the liver.

HYDRAZINE SULFATE Interactions What is this?

Major Interaction Do not take this combination

  • Medications for depression (MAOIs) interacts with HYDRAZINE SULFATE

    Hydrazine sulfate contains a chemical that affects the body. This chemical might increase the side effects of some medications used for depression.
    Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.

  • Sedative medications (CNS depressants) interacts with HYDRAZINE SULFATE

    Hydrazine sulfate might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking hydrazine sulfate along with sedative medications might cause too much sleepiness.
    Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.


Moderate Interaction Be cautious with this combination

  • Isoniazid (INH, Nydrazid) interacts with HYDRAZINE SULFATE

    Isoniazid is a drug used for tuberculosis. The body breaks isoniazid down to hydrazine. Using both isoniazid and hydrazine might increase the risk of liver damage.

  • Medications for diabetes (Antidiabetes drugs) interacts with HYDRAZINE SULFATE

    Hydrazine sulfate might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking hydrazine sulfate along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
    Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.


HYDRAZINE SULFATE Dosing

The appropriate dose of hydrazine sulfate depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for hydrazine sulfate. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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