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SUPEROXIDE DISMUTASE

Other Names:

Orgotein, SOD, Super Dioxide Dismutase, Superóxido Dismutasa, Superoxydase Dismutase, Superoxyde Dismutase.

SUPEROXIDE DISMUTASE Overview
SUPEROXIDE DISMUTASE Uses
SUPEROXIDE DISMUTASE Side Effects
SUPEROXIDE DISMUTASE Interactions
SUPEROXIDE DISMUTASE Dosing
SUPEROXIDE DISMUTASE Overview Information

Superoxide dismutase is an enzyme found in all living cells. An enzyme is a substance that speeds up certain chemical reactions in the body. The superoxide dismutase that is used as medicine is sometimes taken from cows.

Superoxide dismutase is taken by mouth for removing wrinkles, rebuilding tissue, and extending the length of life. However, there is no evidence that superoxide dismutase products that are taken by mouth are absorbed by the body.

As a shot, superoxide dismutase is used for treating pain and swelling (inflammation) caused by osteoarthritis, sports injuries, and rheumatoid arthritis; a kidney condition called interstitial cystitis; gout; poisoning caused by a weed-killer called paraquat; cancer; and lung problems in newborns.

Superoxide dismutase is also given as a shot for improving tolerance to radiation therapy, improving rejection rates in kidney transplantation, and minimizing heart damage caused by heart attacks.

A sterile solution containing superoxide dismutase is sometimes applied directly to the eyes for treating ulcers on the cornea.

How does it work?

Superoxide dismutase is an enzyme that helps break down potentially harmful oxygen molecules in cells, which might prevent damage to tissues. It is being researched to see if it can help conditions where oxygen molecules are believed to play a role in disease.

SUPEROXIDE DISMUTASE Uses & Effectiveness What is this?

Possibly Effective for:



BY INJECTION


Likely Ineffective for:



BY INJECTION

  • Reducing heart damage after a heart attack.

Insufficient Evidence for:

  • Ulcers on the cornea of the eye. A series of case reports suggest that a specific eye solution of superoxide dismutase might help reduce ulcer size and improve healing when applied to the eye for at least 2 weeks.
  • Sports injuries.
  • Gout.
  • Cancer.
  • Helping people tolerate radiation therapy.
  • Preventing rejection of kidney transplants.
  • Other conditions.
More evidence is needed to rate the effectiveness of superoxide dismutase for these uses.


SUPEROXIDE DISMUTASE Side Effects & Safety

Injectable (shot) forms of superoxide dismutase that have been used in research studies appear to be safe. Some superoxide dismutase products are obtained from animal sources, raising concern about contamination from sick or diseased animals. Though there are no reports of people getting sick after using superoxide dismutase products taken from animals, it’s best to avoid products from animal sources until more is known.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of superoxide dismutase during pregnancy and breast-feeding. Stay on the safe side and avoid use.

SUPEROXIDE DISMUTASE Interactions What is this?

We currently have no information for SUPEROXIDE DISMUTASE Interactions

SUPEROXIDE DISMUTASE Dosing

The following doses have been studied in scientific research:

BY INJECTION:

  • Healthcare providers give superoxide dismutase as a shot for certain bladder infections (interstitial cystitis), osteoarthritis, rheumatoid arthritis (RA), and lung damage that sometimes develops in premature infants who have been given oxygen to help them survive.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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