DMAE (DEANOL) Overview Information
Deanol is a chemical that is involved in a series of reactions that form acetylcholine, a chemical that is found in the brain and other areas of the body. Acetylcholine is a “neurotransmitter” that helps nerve cells communicate.
Deanol is used for treating attention deficit-hyperactivity disorder (ADHD), Alzheimer’s disease, autism, and a movement disorder called tardive dyskinesia. It is also used for improving memory and mood; boosting thinking skills and intelligence; and increasing physical energy, oxygen efficiency, athletic performance, and muscle reflexes. It is also used for preventing aging or liver spots, improving red blood cell function, and extending life span.
Deanol is applied to the skin for reducing signs of aging, particularly loose or sagging skin.
Deanol was previously sold by Riker Laboratories as the prescription drug Deaner. It was prescribed for the management of children with behavior problems and learning difficulties. Deanol is not an approved food additive in the U.S., nor is it an orphan drug, as some advertising suggests.
How does it work?
Deanol is needed to build the chemical choline. Having more choline in the body might increase the production of acetylcholine, which is involved in brain and nervous system function.
Possibly Effective for:
Likely Ineffective for:
- Alzheimer's disease.
- Unwanted movements of the face and mouth (tardive dyskinesia).
- Treating aging skin. There is some early evidence that applying a 3% deanol gel to facial skin can tighten sagging skin.
- Treating attention deficit-hyperactivity disorder (ADHD).
- Improving memory and mood.
- Improving intelligence and physical energy.
- Preventing aging or liver spots.
- Improving red blood cell function.
- Improving muscle reflexes.
- Increasing oxygen efficiency.
- Extending life span.
- Treating autism.
- Other conditions.
DMAE (DEANOL) Side Effects & Safety
Deanol is POSSIBLY SAFE for most people when taken by mouth or applied to the skin.
When taken by mouth, deanol can cause constipation, itching, headache, drowsiness, insomnia, excitation, vivid dreams, confusion, depression, increased blood pressure, an increase in schizophrenia symptoms, and unwanted movements of the face and mouth.
Special Precautions & Warnings:Pregnancy and breast-feeding: Not enough is known about the use of deanol during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Clonic-tonic seizures: Deanol should not be used by people with clonic-tonic seizure disorders.
Depression: Deanol might make depression worse.
Schizophrenia: Deanol might make schizophrenia symptoms worse.
Minor Interaction Be watchful with this combination
- Drying medications (Anticholinergic drugs) interacts with DEANOL
Some drying medications are called anticholinergic drugs. Deanol might increase chemicals that can decrease the effects of these drying medications.
Some drying medications include atropine, scopolamine, and some medications used for allergies (antihistamines), and for depression (antidepressants).
- Medications for Alzheimer's disease (Acetylcholinesterase (AChE) inhibitors) interacts with DEANOL
Deanol might increase a chemical in the body called acetylcholine. Medications for Alzheimer's called acetylcholinesterase inhibitors also increase the chemical acetylcholine. Taking deanol along with medications for Alzheimer's disease might increase effects and side effects of medications for Alzheimer's disease.
Some medications called acetylcholinesterase inhibitors include donepezil (Aricept), tacrine (Cognex), rivastigmine (Exelon), and galantamine (Reminyl, Razadyne).
- Various medications used for glaucoma, Alzheimer's disease, and other conditions (Cholinergic drugs) interacts with DEANOL
Deanol might increase a chemical in the body called acetylcholine. This chemical is similar to some medications used for glaucoma, Alzheimer's disease, and other conditions. Taking deanol with these medications might increase the chance of side effects.
Some of these medications used for glaucoma, Alzheimer's disease, and other conditions include pilocarpine (Pilocar and others), and others.
DMAE (DEANOL) Dosing
The following doses have been studied in scientific research:
- For improving exercise performance: 300 to 2000 mg of deanol per day.