TARRAGON - Uses, Side Effects, and More

Benli, M., Kaya, I., and Yigit, N. Screening antimicrobial activity of various extracts of Artemisia dracunculus L. Cell Biochem.Funct. 2007;25(6):681-686. View abstract.

de Pradier E. A trial of a mixture of three essential oils in the treatment of postoperative nausea and vomiting. International Journal of Aromatherapy 2006;16(1):15-20.

De Vincenzi, M., Silano, M., Maialetti, F., and Scazzocchio, B. Constituents of aromatic plants: II. Estragole. Fitoterapia 2000;71(6):725-729. View abstract.

Dohi, S., Terasaki, M., and Makino, M. Acetylcholinesterase Inhibitory Activity and Chemical Composition of Commercial Essential Oils. J Agric.Food Chem. 4-9-2009; View abstract.

Drinkwater, N. R., Miller, E. C., Miller, J. A., and Pitot, H. C. Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria. J Natl.Cancer Inst. 1976;57(6):1323-1331. View abstract.

Engelmeier, D., Hadacek, F., Hofer, O., Lutz-Kutschera, G., Nagl, M., Wurz, G., and Greger, H. Antifungal 3-butylisocoumarins from Asteraceae-Anthemideae. J Nat.Prod. 2004;67(1):19-25. View abstract.

European Medicines Agency, Committee on herbal medicinal products HMPC. Public statement on the use of herbal medicinal products containing estragole.

Govorko, D., Logendra, S., Wang, Y., Esposito, D., Komarnytsky, S., Ribnicky, D., Poulev, A., Wang, Z., Cefalu, W. T., and Raskin, I. Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am.J Physiol Endocrinol.Metab 2007;293(6):E1503-E1510. View abstract.

Haze, S., Sakai, K., and Gozu, Y. Effects of fragrance inhalation on sympathetic activity in normal adults. Jpn.J Pharmacol. 2002;90(3):247-253. View abstract.

Iten, F. and Saller, R. [Fennel tea: risk assessment of the phytogenic monosubstance estragole in comparison to the natural multicomponent mixture]. Forsch.Komplementarmed.Klass.Naturheilkd. 2004;11(2):104-108. View abstract.

Jakupovic, J., Tan, R. X., Bohlmann, F., Jia, Z. J., and Huneck, S. Acetylenes and Other Constituents from Artemisia dracunculus. Planta Med. 1991;57(5):450-453. View abstract.

Kaledin, V. I., Pakharukova, M. Y., Pivovarova, E. N., Kropachev, K. Y., Baginskaya, N. V., Vasilieva, E. D., Ilnitskaya, S. I., Nikitenko, E. V., Kobzev, V. F., and Merkulova, T. I. Correlation between hepatocarcinogenic effect of estragole and its influence on glucocorticoid induction of liver-specific enzymes and activities of FOXA and HNF4 transcription factors in mouse and rat liver. Biochemistry (Mosc.) 2009;74(4):377-384. View abstract.

Kavvadias, D., Abou-Mandour, A. A., Czygan, F. C., Beckmann, H., Sand, P., Riederer, P., and Schreier, P. Identification of benzodiazepines in Artemisia dracunculus and Solanum tuberosum rationalizing their endogenous formation in plant tissue. Biochem.Biophys.Res Commun. 3-5-2000;269(1):290-295. View abstract.

Kordali, S., Kotan, R., Mavi, A., Cakir, A., Ala, A., and Yildirim, A. Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A. dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils. J Agric.Food Chem. 11-30-2005;53(24):9452-9458. View abstract.

Logendra, S., Ribnicky, D. M., Yang, H., Poulev, A., Ma, J., Kennelly, E. J., and Raskin, I. Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry 2006;67(14):1539-1546. View abstract.

Lopes-Lutz, D., Alviano, D. S., Alviano, C. S., and Kolodziejczyk, P. P. Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry 2008;69(8):1732-1738. View abstract.

Meepagala, K. M., Sturtz, G., and Wedge, D. E. Antifungal constituents of the essential oil fraction of Artemisia dracunculus L. Var. dracunculus. J Agric.Food Chem. 11-20-2002;50(24):6989-6992. View abstract.

Mohsenzadeh, M. Evaluation of antibacterial activity of selected Iranian essential oils against Staphylococcus aureus and Escherichia coli in nutrient broth medium. Pak.J Biol.Sci. 10-15-2007;10(20):3693-3697. View abstract.

O'Mahony, R., Al Khtheeri, H., Weerasekera, D., Fernando, N., Vaira, D., Holton, J., and Basset, C. Bactericidal and anti-adhesive properties of culinary and medicinal plants against Helicobacter pylori. World J Gastroenterol. 12-21-2005;11(47):7499-7507. View abstract.

Ribnicky, D. M., Kuhn, P., Poulev, A., Logendra, S., Zuberi, A., Cefalu, W. T., and Raskin, I. Improved absorption and bioactivity of active compounds from an anti-diabetic extract of Artemisia dracunculus L. Int.J Pharm 3-31-2009;370(1-2):87-92. View abstract.

Ribnicky, D. M., Poulev, A., O'Neal, J., Wnorowski, G., Malek, D. E., Jager, R., and Raskin, I. Toxicological evaluation of the ethanolic extract of Artemisia dracunculus L. for use as a dietary supplement and in functional foods. Food Chem.Toxicol 2004;42(4):585-598. View abstract.

Ribnicky, D. M., Poulev, A., Watford, M., Cefalu, W. T., and Raskin, I. Antihyperglycemic activity of Tarralin, an ethanolic extract of Artemisia dracunculus L. Phytomedicine. 2006;13(8):550-557. View abstract.

Saadali, B., Boriky, D., Blaghen, M., Vanhaelen, M., and Talbi, M. Alkamides from Artemisia dracunculus. Phytochemistry 2001;58(7):1083-1086. View abstract.

Sayyah, M., Nadjafnia, L., and Kamalinejad, M. Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil. J Ethnopharmacol. 2004;94(2-3):283-287. View abstract.

Shahriyary, L. and Yazdanparast, R. Inhibition of blood platelet adhesion, aggregation and secretion by Artemisia dracunculus leaves extracts. J Ethnopharmacol. 11-1-2007;114(2):194-198. View abstract.

Smith, R. L., Adams, T. B., Doull, J., Feron, V. J., Goodman, J. I., Marnett, L. J., Portoghese, P. S., Waddell, W. J., Wagner, B. M., Rogers, A. E., Caldwell, J., and Sipes, I. G. Safety assessment of allylalkoxybenzene derivatives used as flavouring substances - methyl eugenol and estragole. Food Chem.Toxicol 2002;40(7):851-870. View abstract.

Swanston-Flatt, S. K., Day, C., Bailey, C. J., and Flatt, P. R. Evaluation of traditional plant treatments for diabetes: studies in streptozotocin diabetic mice. Acta Diabetol.Lat. 1989;26(1):51-55. View abstract.

Thieme, H. and Nguyen, Thi Tam. [Studies on the accumulation and composition of the volatile oils of Satureja hortensis L., Satureja montana L. and Artemisia dracunculus L. during ontogenesis. 2. Changes in the content and composition of the volatile oil]. Pharmazie 1972;27(5):324-331. View abstract.

Thieme, H. and Nguyen, Thi Tam. [Studies on the accumulation and composition of volatile oils in Satureja hortensis L., Satureja montana L. and Artemisia dracunculus L. during ontogenesis. 1. Review of literature, thin-layer and gas-chromatographic studies]. Pharmazie 1972;27(4):255-265. View abstract.

Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. View abstract.

Tsai, P. J., Tsai, T. H., Yu, C. H., and Ho, S. C. Evaluation of NO-suppressing activity of several Mediterranean culinary spices. Food Chem.Toxicol. 2007;45(3):440-447. View abstract.

Vasil'ev, E. D., Il'nitskaia, S. I., Nikitenko, E. V., and Kaledin, V. I. [Age- and sex-related differences in sensitivity to hepatotoxic action of estragole in mice]. Ross.Fiziol.Zh.Im I.M.Sechenova 2005;91(9):1066-1070. View abstract.

Ward, N. I. and Savage, J. M. Metal dispersion and transportational activities using food crops as biomonitors. Sci Total Environ. 5-23-1994;146-147:309-319. View abstract.

Watanabe, J., Shinmoto, H., and Tsushida, T. Coumarin and flavone derivatives from estragon and thyme as inhibitors of chemical mediator release from RBL-2H3 Cells. Biosci.Biotechnol.Biochem. 2005;69(1):1-6. View abstract.

Yazdanparast, R. and Shahriyary, L. Comparative effects of Artemisia dracunculus, Satureja hortensis and Origanum majorana on inhibition of blood platelet adhesion, aggregation and secretion. Vascul.Pharmacol 2008;48(1):32-37. View abstract.

Zhang, Y., Zhang, J., Yao, J., Yang, Y. L., Wang, L., and Dong, L. N. [Studies on the chemical constituents of the essential oil of Artemisia dracunculus]. Zhongguo Zhong.Yao Za Zhi. 2005;30(8):594-596. View abstract.

Allerton TD, Kowalski GM, Stampley J, et al. An Ethanolic Extract of Artemisia dracunculus L. Enhances the Metabolic Benefits of Exercise in Diet-induced Obese Mice. Med Sci Sports Exerc 2021;53(4):712-723. View abstract.

Aydin T, Akincioglu H, Gumustas M, Gulcin I, Kazaz C, Cakir A. Human monoamine oxidase (hMAO) A and hMAO B inhibitors from Artemisia dracunculus L. herniarin and skimmin: human mononamine oxidase A and B inhibitors from A. dracunculus L. Z Naturforsch C J Biosci 2020;75(11-12):459-466. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

Safari H, Anani Sarab G, Naseri M. Artemisia dracunculus L. modulates the immune system in a multiple sclerosis mouse model. Nutr Neurosci 2021;24(11):843-849. View abstract.