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CONJUGATED LINOLEIC ACID

Other Names:

Acide Linoléique Conjugué, Acide Linoléique Conjugué Cis-9,trans-11, Acide Linoléique Conjugué trans-10,cis-12, Acido Linoleico Conjugado, ALC, Cis-9,trans-11 Conjugated Linoleic Acid, Cis-Linoleic Acid, CLA, CLA-Free Fatty Acid, CLA-Triacylglyc...
See All Names

 Overview
 Uses
 Side Effects
 Interactions
 Dosing
Overview Information

Conjugated linoleic acid refers to a group of chemicals found in the fatty acid linoleic acid. Dairy products and beef are the major dietary sources.

Conjugated linoleic acid is used for cancer, “hardening of the arteries” (atherosclerosis), obesity, weight loss caused by chronic disease, bodybuilding, and limiting food allergy reactions.

An average diet supplies 15-174 mg of conjugated linoleic acid daily.

How does it work?

Conjugated linoleic acid might help reduce body fat deposits and improve immune function.

Uses & Effectiveness What is this?

Possibly Effective for:

  • Colon and rectal cancer. Some research suggests that a diet high in conjugated linoleic acid might reduce the risk of cancer of the colon and rectum in women. It is not known whether taking conjugated linoleic acid supplements provides the same benefit.
  • Obesity. Conjugated linoleic acid might help decrease body fat, but it does not seem to decrease body weight.

Insufficient Evidence for:

  • Breastcancer. There is preliminary evidence that conjugated linoleic acid might help prevent breast cancer. Women who have passed menopause and have a higher intake of conjugated linoleic acid from foods, particularly cheese, seem to have a lower risk of developing breast cancer.
  • Bodybuilding.
  • Reducing cholesterol levels.
  • Other conditions.
More evidence is needed to rate conjugated linoleic acid for these uses.


Side Effects & Safety

Conjugated linoleic acid is LIKELY SAFE when used in amounts found in foods and is POSSIBLY SAFE for use in medicinal amounts (larger amounts than those found in food). It might cause side effects such as stomach upset, diarrhea, nausea, and fatigue.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of conjugated linoleic acid in medicinal mounts during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Diabetes: There are concerns that taking conjugated linoleic acid can worsen diabetes. Avoid use.

Metabolic syndrome: There are concerns that taking conjugated linoleic acid might increase the risk of getting diabetes if you have metabolic syndrome. Avoid use.

Interactions What is this?

We currently have no information for Interactions

Dosing

The following doses have been studied in scientific research:

BY MOUTH

  • For reducing body fat in obese patients, a dose of 1.8 to 7 grams per day has been used. However, doses greater than 3.4 grams per day do not seem to offer any additional benefit.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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