Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Find a Vitamin or Supplement


Other Names:

American Skullcap, Blue Pimpernel, Blue Skullcap, Escutelaria, Grande Toque, Helmet Flower, Hoodwort, Mad-Dog Herb, Mad-Dog Skullcap, Mad-Dog Weed, Mad Weed, Quaker Bonnet, Scullcap, Scutellaria, Scutellaire, Scutellaire de Virginie, Scutellaire...
See All Names

SKULLCAP Side Effects
SKULLCAP Interactions
SKULLCAP Overview Information

Skullcap is a plant. The above ground parts are used to make medicine.

Skullcap is used for many conditions, but so far, there isn’t enough scientific evidence to determine whether or not it is effective for any of them.

Skullcap is used for trouble sleeping (insomnia), anxiety, stroke, and paralysis caused by stroke. It is also used for fever, high cholesterol, “hardening of the arteries” (atherosclerosis), rabies, epilepsy, nervous tension, allergies, skin infections, inflammation, and spasms.

Skullcap products are not always what the labels claim. The plants germander and teucrium are often unwanted and unlabeled ingredients in skullcap products. Secondly, you may think you are buying Scuttelaria lateriflora, the species of skullcap that has been studied for medicinal use, but the product may contain a different species of skullcap instead. The most often substituted species are Western Skullcap (Scuttelaria canescens), Southern Skullcap (Scutellaria cordifolia), or Marsh Skullcap (Scutellaria galericulatum). These species contain different chemicals, so they are not considered interchangeable.

How does it work?

The chemicals in skullcap might work by preventing swelling (inflammation). Other chemicals in skullcap are thought to cause sedation (drowsiness).

SKULLCAP Uses & Effectiveness What is this?

Insufficient Evidence for:

  • Anxiety. Limited evidence suggests that healthy people who take a single dose of skullcap extract might feel more relaxed than tense. This effect appears to last for about 2 hours. However, it is not known if taking skullcap is effective for anxiety disorders or if extended use is beneficial.
  • Seizures.
  • Trouble sleeping (insomnia).
  • Stroke.
  • Other conditions.
More evidence is needed to rate the effectiveness of skullcap for these uses.

SKULLCAP Side Effects & Safety

There is not enough information available to know if skullcap is safe to take for medical conditions.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking skullcap is you are pregnant or breast feeding. Stay on the safe side and avoid use.

Surgery: Skullcap may slow down the central nervous system. Healthcare providers worry that anesthesia and other medications during and after surgery might increase this effect. Stop taking skullcap at least 2 weeks before a scheduled surgery.

SKULLCAP Interactions What is this?

We currently have no information for SKULLCAP Interactions


The appropriate dose of skullcap depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for skullcap. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

See 19 Reviews for this Treatment - OR -

Review this Treatment

Learn about User Reviews and read IMPORTANT information about user generated content

Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

Search for a Vitamin or Supplement

Ex. Ginseng, Vitamin C, Depression

Today on WebMD

vitamin rich groceries
Do you know your vitamin ABCs?
St Johns wart
Ease hot flashes and other symptoms.
Are you getting enough?
Take your medication
Wonder pill or overkill?
fruits and vegetables
Woman sleeping
Woman staring into space with coffee
IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.