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    6 Symptoms You Shouldn't Ignore

    3. Tenderness and Pain in the Back of Your Lower Leg

    This can be a symptom of a blood clot in your leg. It's called deep vein thrombosis, or DVT. It can happen after you've been sitting for a long time, like on a long plane ride, or if you're sick and have been in bed a long time.

    If it's a blood clot, you may feel the pain mostly when you stand or walk. You may also notice swelling.

    It's normal to feel tenderness after exercise. But if you also see redness and feel heat where it's swollen or painful, call your doctor.

    Teitelbaum says you can also check for what's called the Homans sign. "If you flex your toes upward and it hurts, that's also suggestive of a blood clot," he says. "But don't rely on that. If it's hot, red, and swollen on one side, go to the ER."

    It's important to catch a blood clot before it can break off and block your blood flow, which can lead to complications.

    4. Blood in Your Urine

    Several things can cause you to see blood when you pee.

    If you have blood in your urine and you also feel a lot of pain in your side or in your back, you may have kidney stones. A kidney stone is a small crystal made of minerals and salts that forms in your kidney and moves through the tube that carries your urine.

    Your doctor may take X-rays or do an ultrasound to see the stones. An X-ray uses radiation in low doses to make images of structures inside your body. An ultrasound makes images with sound waves.

    Many kidney stones eventually pass through your body when you pee. Sometimes your doctor may need to remove the kidney stone.

    If you see blood in your urine and you also have an increase in feeling that you urgently need to pee, make frequent trips to the bathroom, or feel burning when you urinate, you may have a severe bladder or kidney infection, Teitelbaum says. Don't wait to see your doctor, especially if you have a fever.

    If you see blood but don't feel any pain, it may be a sign of kidney or bladder cancer, so visit your doctor.

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