Oprah and Bioidentical Hormones: FAQ
Oprah Is Talking About Bioidentical Hormones for Menopause; Experts Weigh In
WebMD News Archive
Jan. 15, 2009 -- Oprah Winfrey says menopause caught her "off guard"
and that she's taking bioidentical hormones that have made a big improvement in
how she feels.
Bioidentical hormones are one form of therapy for menopausal symptoms.
Winfrey, who turns 55 this month, writes in February's edition of O, The
Oprah Magazine that she felt "out of kilter" and had
"issues" for two years that she suspected were hormonal. Upon a
friend's recommendation, Winfrey went to a doctor who specializes in
Winfrey writes that the hormone specialist told her that her "hormonal
tank was empty" and gave her a prescription for bioidentical estrogen.
"After one day on bioidentical estrogen, I felt the veil lift,"
Winfrey writes. "After three days, the sky was bluer, my brain was no
longer fuzzy, my memory was sharper. I was literally singing and had a skip in
Winfrey isn't recommending bioidentical hormones for every menopausal woman.
Instead, she urges women to "take charge of your health" and says it's
time to "start the conversation" about menopause and bioidentical
Oprah writes that bioidentical hormone therapy is controversial and
confusing to many people.
What's the controversy about? Are bioidentical hormones better or safer than
other hormone therapy? WebMD has answers from experts.
What Are Bioidentical Hormones?
"There is enormous confusion about the meaning of the term
'bioidentical,'" JoAnn Manson, MD, DrPH, tells WebMD via email.
"Bioidentical hormone preparations are medications that contain hormones that are an exact
chemical match to those made naturally by humans," says Manson, who is
chief of preventive medicine at Brigham and Women's Hospital in Boston and the
Elizabeth F. Brigham Professor of Women's Health at Harvard Medical School.
Some bioidentical hormones are made by drug companies, are approved by the
FDA, and are sold in standard doses. Other bioidentical hormone preparations
are made at special pharmacies called compounding pharmacies, which make the
preparations on a case-by-case basis for each patient. Those
"custom-made" preparations aren't approved by the FDA.
Why Aren't Compounded Bioidentical Hormones FDA approved?
The FDA doesn't approve any compounded products, for any condition, because
those products aren't standardized.